Lactococcus lactis as an Interleukin Delivery System for Prophylaxis and Treatment of Inflammatory and Autoimmune Diseases

GM Campos, MF Américo, A dos Santos Freitas… - Probiotics and …, 2024 - Springer
Target delivery of therapeutic agents with anti-inflammatory properties using probiotics as
delivery and recombinant protein expression vehicles is a promising approach for the …

Lactobacillus paracasei CNCM I 1572: A Promising Candidate for Management of Colonic Diverticular Disease

E Bretto, F D'Amico, W Fiore, A Tursi… - Journal of Clinical …, 2022 - mdpi.com
Diverticular disease (DD) is a common gastrointestinal condition. Patients with DD
experience a huge variety of chronic nonspecific symptoms, including abdominal pain …

[HTML][HTML] Immunostimulatory effects of dairy probiotic strains Bifidobacterium animalis ssp. lactis HY8002 and Lactobacillus plantarum HY7717

JY Kim, JY Kim, H Kim, EC Moon, K Heo… - Journal of Animal …, 2022 - ncbi.nlm.nih.gov
Previous studies reported that Bifidobacterium animalis ssp. lactis HY8002 (HY8002)
improved intestinal integrity and had immunomodulatory effects. Lactobacillus plantarum …

Gut commensal Limosilactobacillus reuteri induces atypical memory-like phenotype in human dendritic cells in vitro

G Lasaviciute, M Barz, M van Der Heiden, C Arasa… - Gut …, 2022 - Taylor & Francis
Memory-like responses in innate immune cells confer nonspecific protection against
secondary exposures. A number of microbial agents have been found to induce enhanced …

Trained innate immunity, epigenetics, and food allergy

L Arzola-Martínez, C Ptaschinski, NW Lukacs - Frontiers in Allergy, 2023 - frontiersin.org
In recent years the increased incidence of food allergy in Western culture has been
associated with environmental factors and an inappropriate immune phenotype. While the …

Cellular carcinogenesis: Role of polarized macrophages in cancer initiation

RB Undi, A Filiberti, N Ali, MM Huycke - Cancers, 2022 - mdpi.com
Simple Summary Inflammation is a hallmark of many cancers. Macrophages are key
participants in innate immunity and important drivers of inflammation. When chronically …

Development of innate immune memory by non-immune cells during Staphylococcus aureus infection depends on reactive oxygen species

E Chaumond, S Peron, N Daniel, Y Le Gouar… - Frontiers in …, 2023 - frontiersin.org
Introduction The mechanisms underlying innate immune memory (trained immunity)
comprise epigenetic reprogramming of transcriptional pathways associated with alterations …

Microbial characterization of the nasal cavity in patients with allergic rhinitis and non-allergic rhinitis

Y Che, N Wang, Q Ma, J Liu, Z Xu, Q Li… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Although recent studies have shown that the human microbiome is involved in
the pathogenesis of allergic diseases, the impact of microbiota on allergic rhinitis (AR) and …

Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii served as key components of fecal microbiota transplantation to alleviate colitis

B Xu, Y Fu, N Yin, W Qin, Z Huang… - American Journal …, 2024 - journals.physiology.org
Fecal microbiota transplantation (FMT) is a promising therapy for inflammatory bowel
disease (IBD) via rectifying gut microbiota. The aim of this study was to identify a mechanism …

Non-specific effects of inactivated Mycobacterium bovis oral and parenteral treatment in a rabbit scabies model

R Casais, N Iglesias, IA Sevilla, JM Garrido… - Veterinary …, 2024 - Springer
Tuberculosis BCG vaccination induced non-specific protective effects in humans led to
postulate the concept of trained immunity (TRAIM) as an innate type of immune mechanism …