CRISPR‐Cas are adaptable natural prokaryotic defense systems that act against invading
viruses and plasmids. Among the six currently known major CRISPR‐Cas types, the type VI …

Clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated
protein (Cas) systems, especially type II (Cas9) systems, have been widely developed for …

A major challenge in coronavirus vaccination and treatment is to counteract rapid viral
evolution and mutations. Here we demonstrate that CRISPR-Cas13d offers a broad …

Background RNA viruses account for many human diseases and pandemic events but are
often not targetable by traditional therapeutics modalities. Here, we demonstrate that adeno …

The hepatitis B virus (HBV) continues to cause substantial health and economic burdens,
and its target of elimination may not be reached in 2030 without further efforts in diagnostics …

CRISPR-Cas13-mediated viral genome targeting is a novel strategy for defending against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Here, we …

The ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 570 …

As CRISPR/Cas systems have been refined over time, there has been an effort to apply
them to real world problems, such as developing sequence-targeted antiviral therapies …

Grapevine leafroll-associated virus 3 (GLRaV-3) is one of the causal agents of grapevine
leafroll disease (GLD), which severely impacts grapevine production in most viticultural …

The CRISPR/Cas system, identified as a type of bacterial adaptive immune system, have
attracted significant attention due to its remarkable ability to precisely detect and eliminate …