1. Cell Culture Approach to the Study of Granulosa Cells In 1672, Regnier de Graaf first
described the differentiation of ovarian follicles into the corpus luteum. He stated that “age …

Using a semi-quantitative review of published electron micrographs, we have explored the
passage of mitochondria from one generation to the next through the cytoplasm of the …

The expansion, or mucification, of the mouse cumulus oophorus in vitro requires the
presence of an enabling factor secreted by the oocyte as well as stimulation with follicle …

Although it has been shown that granulosa cells regulate the growth and meiotic maturation
of mammalian oocytes, there is little evidence of a role for the oocyte in the differentiation or …

The efficacy of follicle‐stimulating hormone (FSH), epidermal growth factor (EGF), and
dibutyryl cGMP (dbcGMP) as inducers of germinal vesicle breakdown (GVBD) in cumulus …

Natriuretic peptide type C (NPPC) and its cognate receptor natriuretic peptide receptor 2
(NPR2) are essential for maintaining meiotic arrest in mouse oocytes residing in Graafian …

Studies were carried out to identify and quantify the porcine follicular fluid (PFF) component
(s) responsible for inhibition of murine oocyte maturation. A low molecular weight fraction of …

Abstract Bovine follicular oocytes (N= 5991) were exposed to an analog of cyclic adenosine
3′, 5′-monophosphate (cAMP), dibutyryl cyclic AMP (db-cAMP)(2.5, 5, and 10 mM), the …

Interactions between the cumulus-oophorus and the oocyte have been implicated in the
regulation of meiotic maturation. Quantitative analysis of freeze-fractured rat cumulus-oocyte …

Porcine follicular oocytes, collected from antral follicles (2–5 mm in diameter) of gilt ovaries,
were matured in vitro with or without porcine follicular fluid (pFF), gonadotrophins (GTH) or …