[HTML][HTML] The role of Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) as m6A readers in cancer
CY Sun, D Cao, BB Du, CW Chen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
RNA can be modified by over 170 types of distinct chemical modifications, and the most
abundant internal modification of mRNA in eukaryotes is N6-methyladenosine (m 6 A). The …
abundant internal modification of mRNA in eukaryotes is N6-methyladenosine (m 6 A). The …
[HTML][HTML] RNA modification in cardiovascular disease: implications for therapeutic interventions
C Wang, X Hou, Q Guan, H Zhou, L Zhou… - … and Targeted Therapy, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death in the world, with a high
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …
Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury
Acute kidney injury (AKI) is a major risk factor for long-term adverse outcomes, including
chronic kidney disease. In mouse models of AKI, maladaptive repair of the injured proximal …
chronic kidney disease. In mouse models of AKI, maladaptive repair of the injured proximal …
Neutrophil Membrane‐Camouflaged Polyprodrug Nanomedicine for Inflammation Suppression in Ischemic Stroke Therapy
Y Zhao, Q Li, J Niu, E Guo, C Zhao, J Zhang… - Advanced …, 2024 - Wiley Online Library
Neuroinflammation has emerged as a major concern in ischemic stroke therapy because it
exacebates neurological dysfunction and suppresses neurological recovery after …
exacebates neurological dysfunction and suppresses neurological recovery after …
[HTML][HTML] Single-cell N6-methyladenosine regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer …
Y Gao, H Wang, S Chen, R An, Y Chu, G Li… - Journal of Translational …, 2022 - Springer
Abstract Background N6-methyladenosine (m6A) RNA methylation plays a critical role in key
genetic events for various cancers; yet, how m6A functions within the tumor …
genetic events for various cancers; yet, how m6A functions within the tumor …
The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers
AC Grenov, L Moss, S Edelheit, R Cordiner… - Journal of Experimental …, 2021 - rupress.org
Long-lasting immunity depends on the generation of protective antibodies through the
germinal center (GC) reaction. N 6-methyladenosine (m6A) modification of mRNAs by …
germinal center (GC) reaction. N 6-methyladenosine (m6A) modification of mRNAs by …
[HTML][HTML] Immune cells in the epithelial immune microenvironment of psoriasis: emerging therapeutic targets
L Li, J Lu, J Liu, J Wu, X Zhang, Y Meng, X Wu… - Frontiers in …, 2024 - frontiersin.org
Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …
[HTML][HTML] Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization
P Liu, Y Chen, Z Zhang, Z Yuan, JG Sun, S Xia… - PLoS …, 2023 - journals.plos.org
Microglia-mediated neuroinflammation is involved in various neurological diseases,
including ischemic stroke, but the endogenous mechanisms preventing unstrained …
including ischemic stroke, but the endogenous mechanisms preventing unstrained …
[HTML][HTML] YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation
Antibody-mediated immunity is initiated by B cell differentiation into multiple cell subsets,
including plasmablast, memory, and germinal center (GC) cells. B cell differentiation …
including plasmablast, memory, and germinal center (GC) cells. B cell differentiation …
RNA N6‐methyladenosine modifications and potential targeted therapeutic strategies in kidney disease
WJ Ni, H Lu, NN Ma, BB Hou, J Zeng… - British Journal of …, 2023 - Wiley Online Library
Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …
extensively involved in kidney development and disease progression. Among them, the …