RNA can be modified by over 170 types of distinct chemical modifications, and the most
abundant internal modification of mRNA in eukaryotes is N6-methyladenosine (m 6 A). The …

Cardiovascular disease (CVD) is the leading cause of death in the world, with a high
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …

Acute kidney injury (AKI) is a major risk factor for long-term adverse outcomes, including
chronic kidney disease. In mouse models of AKI, maladaptive repair of the injured proximal …

Neuroinflammation has emerged as a major concern in ischemic stroke therapy because it
exacebates neurological dysfunction and suppresses neurological recovery after …

Abstract Background N6-methyladenosine (m6A) RNA methylation plays a critical role in key
genetic events for various cancers; yet, how m6A functions within the tumor …

Long-lasting immunity depends on the generation of protective antibodies through the
germinal center (GC) reaction. N 6-methyladenosine (m6A) modification of mRNAs by …

Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …

Microglia-mediated neuroinflammation is involved in various neurological diseases,
including ischemic stroke, but the endogenous mechanisms preventing unstrained …

Antibody-mediated immunity is initiated by B cell differentiation into multiple cell subsets,
including plasmablast, memory, and germinal center (GC) cells. B cell differentiation …

Epigenetic modifications have received increasing attention and have been shown to be
extensively involved in kidney development and disease progression. Among them, the …