The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Mitochondria are essential organelles in physiology and kidney diseases, because they
produce cellular energy required to perform their function. During mitochondrial metabolism …

Ferroptosis is an iron-dependent, oxidative cell death, and is characterized by iron-
dependent accumulation of reactive oxygen species (ROS) within the cell. It has been …

Hydrogen sulfide (H 2 S) was initially recognized as a toxic gas and its biological functions
in mammalian cells have been gradually discovered during the past decades. In the latest …

Introduction Kidney tubular epithelial injury is one of the key factors in the progression of
diabetic nephropathy (DN). Wogonin is a kind of flavonoid, which has many …

Significance: Hydrogen sulfide (H2S), the third member of the gasotransmitter family, has a
broad spectrum of biological activities, including antioxidant and cytoprotective actions, as …

Hydrogen sulfide (H2S) plays a key role in the regulation of physiological processes in
mammals. The decline in H2S level has been reported in numerous renal disorders. In …

Abstract Hydrogen sulfide (H2S), an endogenous gaseous signaling transmitter, has gained
recognition for its physiological effects. In this review, we aim to summarize and discuss …

Background: Autophagy, as an indispensable metabolism, plays pivotal roles in maintaining
intracellular homeostasis. Nutritional stress, amino acid deficiency, oxidative stress, and …

Renal fibrosis is a key pathological feature in chronic kidney diseases (CKDs).
Dysregulation of hydrogen sulfide (H 2 S) homeostasis is implicated in the pathogenesis of …