The roles of autophagy in cancer

CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

Autophagy as a molecular target for cancer treatment

NM Kocaturk, Y Akkoc, C Kig, O Bayraktar… - European Journal of …, 2019 - Elsevier
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway

Y Fu, H Chang, X Peng, Q Bai, L Yi, Y Zhou, J Zhu… - PloS one, 2014 - journals.plos.org
Resveratrol, a natural polyphenolic compound, is abundantly found in plant foods and has
been extensively studied for its anti-cancer properties. Given the important role of CSCs …

Mechanistic investigation on the toxicity of MgO nanoparticles toward cancer cells

K Krishnamoorthy, JY Moon, HB Hyun… - Journal of materials …, 2012 - pubs.rsc.org
Magnesium oxide nanoparticles (MgO NPs) are increasingly recognized for their
applications in cancer therapy such as nano-cryosurgery and hyperthermia. The present …

Pro-survival autophagy and cancer cell resistance to therapy

CK Das, M Mandal, D Kögel - Cancer and Metastasis Reviews, 2018 - Springer
Resistance to therapy is one of the prime causes for treatment failure in cancer and recurrent
disease. In recent years, autophagy has emerged as an important cell survival mechanism …

Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview

AST Wong, CM Che, KW Leung - Natural product reports, 2015 - pubs.rsc.org
Covering: 2000 to 2014 Cancer is one of the leading causes of death worldwide. Ginseng, a
key ingredient in traditional Chinese medicine, shows great promise as a new treatment …

Autophagy: cancer's friend or foe?

SK Bhutia, S Mukhopadhyay, N Sinha, DN Das… - Advances in cancer …, 2013 - Elsevier
The functional relevance of autophagy in tumor formation and progression remains
controversial. Autophagy can promote tumor suppression during cancer initiation and …

Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells

Q Wu, J Deng, D Fan, Z Duan, C Zhu, R Fu… - Biochemical …, 2018 - Elsevier
The use of ginsenosides in cancer therapy has been intensively investigated. The
ginsenoside Rh4 (Rh4), a rare saponin obtained from Panax notoginseng, dissolves in …

Disinfection of drinking water via algae mediated green synthesized copper oxide nanoparticles and its toxicity evaluation

P Bhattacharya, S Swarnakar, S Ghosh… - Journal of …, 2019 - Elsevier
Industrial and domestic discharges are contaminating surface water via bacterial
infestations. Therefore, the present study focused on application of biogenically derived …

Ginsenosides in cancer: Targeting cell cycle arrest and apoptosis

MA Shah, SM Abuzar, K Ilyas, I Qadees, M Bilal… - Chemico-biological …, 2023 - Elsevier
Despite the existence of extensive clinical research and novel therapeutic treatments,
cancer remains undefeated and the significant cause of death worldwide. Cancer is a …