Neuroimmune interactions: from the brain to the immune system and vice versa

R Dantzer - Physiological reviews, 2018 - journals.physiology.org
Because of the compartmentalization of disciplines that shaped the academic landscape of
biology and biomedical sciences in the past, physiological systems have long been studied …

Glucocorticoids in T cell development, differentiation and function

MD Taves, JD Ashwell - Nature Reviews Immunology, 2021 - nature.com
Glucocorticoids (GCs) are small lipid hormones produced by the adrenals that maintain
organismal homeostasis. Circadian and stress-induced changes in systemic GC levels …

Control of immunity by glucocorticoids in health and disease

A Shimba, K Ikuta - Seminars in Immunopathology, 2020 - Springer
Animals receive environmental stimuli from neural signals in order to produce hormones that
control immune responses. Glucocorticoids (GCs) are a group of steroid hormones …

Intestinal epithelial cells: at the interface of the microbiota and mucosal immunity

AT Soderholm, VA Pedicord - Immunology, 2019 - Wiley Online Library
The intestinal epithelium forms a barrier between the microbiota and the rest of the body. In
addition, beyond acting as a physical barrier, the function of intestinal epithelial cells (IEC s) …

The physiology of the gastric parietal cell

AC Engevik, I Kaji, JR Goldenring - Physiological reviews, 2020 - journals.physiology.org
Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food,
absorption of minerals, and control of harmful bacteria. However, a fine balance of activators …

The cancer-immune dialogue in the context of stress

Y Ma, G Kroemer - Nature Reviews Immunology, 2024 - nature.com
Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Intestinal flora modulates blood pressure by regulating the synthesis of intestinal-derived corticosterone in high salt-induced hypertension

X Yan, J Jin, X Su, X Yin, J Gao, X Wang… - Circulation …, 2020 - Am Heart Assoc
Rationale: High-salt diet is one of the most important risk factors for hypertension. Intestinal
flora has been reported to be associated with high salt–induced hypertension (hSIH) …

TGR5-mediated bile acid sensing controls glucose homeostasis

C Thomas, A Gioiello, L Noriega, A Strehle, J Oury… - Cell metabolism, 2009 - cell.com
TGR5 is a G protein-coupled receptor expressed in brown adipose tissue and muscle,
where its activation by bile acids triggers an increase in energy expenditure and attenuates …

[HTML][HTML] Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs

A Mukherji, A Kobiita, T Ye, P Chambon - Cell, 2013 - cell.com
Alterations of symbiosis between microbiota and intestinal epithelial cells (IEC) are
associated with intestinal and systemic pathologies. Interactions between bacterial products …

[HTML][HTML] Microbial modulation of energy availability in the colon regulates intestinal transit

A Wichmann, A Allahyar, TU Greiner, H Plovier… - Cell host & …, 2013 - cell.com
Gut microbiota contribute to host metabolic efficiency by increasing energy availability
through the fermentation of dietary fiber and production of short-chain fatty acids (SCFAs) in …