[HTML][HTML] Renal tubule injury: a driving force toward chronic kidney disease
Renal tubules are the major component of the kidney and are vulnerable to a variety of
injuries including hypoxia, proteinuria, toxins, metabolic disorders, and senescence. It has …
injuries including hypoxia, proteinuria, toxins, metabolic disorders, and senescence. It has …
Pentraxins: structure, function, and role in inflammation
TW Du Clos - International Scholarly Research Notices, 2013 - Wiley Online Library
The pentraxins are an ancient family of proteins with a unique architecture found as far back
in evolution as the Horseshoe crab. In humans the two members of this family are C‐reactive …
in evolution as the Horseshoe crab. In humans the two members of this family are C‐reactive …
Dissociation of C-reactive protein localizes and amplifies inflammation: evidence for a direct biological role of C-reactive protein and its conformational changes
JD McFadyen, J Kiefer, D Braig, J Loseff-Silver… - Frontiers in …, 2018 - frontiersin.org
C-reactive protein (CRP) is a member of the pentraxin superfamily that is widely recognized
as a marker of inflammatory reactions and cardiovascular risk in humans. Recently, a …
as a marker of inflammatory reactions and cardiovascular risk in humans. Recently, a …
C-reactive protein and its structural isoforms: an evolutionary conserved marker and central player in inflammatory diseases and beyond
JD McFadyen, J Zeller, LA Potempa… - … , lipoproteins and other …, 2020 - Springer
C-reactive protein (CRP) is an evolutionary highly conserved member of the pentraxin
superfamily of proteins. CRP is widely used as a marker of inflammation, infection and for …
superfamily of proteins. CRP is widely used as a marker of inflammation, infection and for …
Therapeutics targeting persistent inflammation in chronic kidney disease
Systemic inflammation is a condition intrinsically linked to chronic kidney disease (CKD) and
its other typical sequelae, such as acquired immune dysfunction, protein-energy wasting …
its other typical sequelae, such as acquired immune dysfunction, protein-energy wasting …
How tubular epithelial cell injury contributes to renal fibrosis
BC Liu, TT Tang, LL Lv - Renal fibrosis: mechanisms and therapies, 2019 - Springer
The renal tubules are the major component of the kidney and are vulnerable to a variety of
injuries including ischemia, proteinuria, toxins, and metabolic disorders. It has long been …
injuries including ischemia, proteinuria, toxins, and metabolic disorders. It has long been …
Estrogen and estrogen receptors in kidney diseases
HY Ma, S Chen, Y Du - Renal failure, 2021 - Taylor & Francis
Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to
global health within this century. Studies have suggested that estrogen and estrogen …
global health within this century. Studies have suggested that estrogen and estrogen …
[HTML][HTML] Inflammatory stress in SARS-COV-2 associated acute kidney injury
J Chen, W Wang, Y Tang, XR Huang… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Increasing clinical evidence shows that acute kidney injury (AKI) is a common and severe
complication in critically ill COVID-19 patients. The older age, the severity of COVID-19 …
complication in critically ill COVID-19 patients. The older age, the severity of COVID-19 …
Therapeutic lowering of C-reactive protein
RV Jimenez, AJ Szalai - Frontiers in immunology, 2021 - frontiersin.org
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas
its blood concentration can rise robustly and rapidly in response to tissue damage and …
its blood concentration can rise robustly and rapidly in response to tissue damage and …
The pentraxins 1975–2018: serendipity, diagnostics and drugs
MB Pepys - Frontiers in immunology, 2018 - frontiersin.org
The phylogenetically ancient, pentraxin family of plasma proteins, comprises C-reactive
protein (CRP) and serum amyloid P component (SAP) in humans and the homologous …
protein (CRP) and serum amyloid P component (SAP) in humans and the homologous …