Abstract Chagas disease and Human African trypanosomiasis (HAT) are caused by
Trypanosoma cruzi, T. brucei rhodesiense or T. b. gambiense parasites, respectively; while …

In this dispensation of rapid scientific and technological advancements, significant efforts are
being made to curb health-related diseases. Research discoveries have highlighted the …

Toxoplasmosis may become a fatal disease in immunodeficient, diabetic patients, pregnant
women, and infants. Hence, the diligent search for new effective treatment is among the …

Focused bis-pyridinium based-ionic liquids were successfully synthesized through the
quaternization of the selected 1, 2-di (pyridin-4-yl) ethane followed by metathetical anion …

Abstract Thirty-five novel 1, 3, 4-thiadiazole-S-alkyl derivatives based on quinazolinone
have been designed and synthesized. The structures of the target compounds 5a− 5p and …

Cancer, a life-threatening condition which has become one of the deadliest disease
impacting human health. Conventional drugs have significant side effects and are prone to …

Parasitic infections such as lymphatic filariasis (elephantiasis) solely result from the
infestation of a slender and thread-like worm. This condition precipitates swelling, often …

Congenital toxoplasmosis is among the leading causes of fetus damage and abortion.
Pyrimethamine+ sulfadiazine is usually the chosen treatment against toxoplasmosis during …

Cardiovascular diseases (CVD) such as heart failure, stroke, and hypertension affect 64.3
million people worldwide and are responsible for 30% of all deaths. Primary inhibition of the …

Cholera has become one of the major global health challenges, especially in sub-Saharan
Africa, where there is poor hygiene and sanitation, and due to the emergence of a resistant …