Viral membrane fusion: a dance between proteins and lipids
There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …
members of high concern for global human health. All enveloped viruses have a dedicated …
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases
T Braulke, JE Carette, W Palm - Trends in Cell Biology, 2024 - cell.com
Lysosomes degrade and recycle macromolecules that are delivered through the
biosynthetic, endocytic, and autophagic routes. Hydrolysis of the different classes of …
biosynthetic, endocytic, and autophagic routes. Hydrolysis of the different classes of …
Can large language models democratize access to dual-use biotechnology?
EH Soice, R Rocha, K Cordova, M Specter… - arXiv preprint arXiv …, 2023 - arxiv.org
Large language models (LLMs) such as those embedded in'chatbots' are accelerating and
democratizing research by providing comprehensible information and expertise from many …
democratizing research by providing comprehensible information and expertise from many …
[HTML][HTML] Predicting zoonotic potential of viruses: where are we?
N Mollentze, DG Streicker - Current Opinion in Virology, 2023 - Elsevier
Highlights•Models predict zoonotic risk using viral traits, host range or genome
composition.•Input data availability defines prospects for zoonosis prediction before …
composition.•Input data availability defines prospects for zoonosis prediction before …
The neonatal Fc receptor (FcRn) is a pan-arterivirus receptor
TM Shaw, D Huey, M Mousa-Makky… - Nature …, 2024 - nature.com
Arteriviruses infect a variety of mammalian hosts, but the receptors used by these viruses to
enter cells are poorly understood. We identified the neonatal Fc receptor (FcRn) as an …
enter cells are poorly understood. We identified the neonatal Fc receptor (FcRn) as an …
Convergent evolution dynamics of SARS-CoV-2 and HIV surface envelope glycoproteins driven by host cell surface receptors and lipid rafts: lessons for the future
Although very different, in terms of their genomic organization, their enzymatic proteins, and
their structural proteins, HIV and SARS-CoV-2 have an extraordinary evolutionary potential …
their structural proteins, HIV and SARS-CoV-2 have an extraordinary evolutionary potential …
A vaccine strategy based on the identification of an annular ganglioside binding motif in Monkeypox virus protein E8L
The recent outbreak of Monkeypox virus requires the development of a vaccine specifically
directed against this virus as quickly as possible. We propose here a new strategy based on …
directed against this virus as quickly as possible. We propose here a new strategy based on …
Viruses of free-roaming and hunting dogs in Uganda show elevated prevalence, richness and abundance across a gradient of contact with wildlife
DS Tayebwa, D Hyeroba, CD Dunn… - Journal of General …, 2024 - microbiologyresearch.org
Domestic dogs (Canis lupus familiaris) live with humans, frequently contact other animals
and may serve as intermediary hosts for the transmission of viruses. Free-roaming dogs …
and may serve as intermediary hosts for the transmission of viruses. Free-roaming dogs …
Will releasing the weights of large language models grant widespread access to pandemic agents?
A Gopal, N Helm-Burger, L Justen, EH Soice… - arXiv preprint arXiv …, 2023 - arxiv.org
Large language models can benefit research and human understanding by providing
tutorials that draw on expertise from many different fields. A properly safeguarded model will …
tutorials that draw on expertise from many different fields. A properly safeguarded model will …