The Drosophila imd signaling pathway

H Myllymäki, S Valanne, M Rämet - The Journal of Immunology, 2014 - journals.aai.org
The fruit fly, Drosophila melanogaster, has helped us to understand how innate immunity is
activated. In addition to the Toll receptor and the Toll signaling pathway, the Drosophila …

[HTML][HTML] Peptidoglycan muropeptides: release, perception, and functions as signaling molecules

O Irazoki, SB Hernandez, F Cava - Frontiers in microbiology, 2019 - frontiersin.org
Peptidoglycan (PG) is an essential molecule for the survival of bacteria, and thus, its
biosynthesis and remodeling have always been in the spotlight when it comes to the …

Procuring the nano-scale lignin in prehydrolyzate as ingredient to prepare cellulose nanofibril composite film with multiple functions

C Huang, H Dong, Z Zhang, H Bian, Q Yong - Cellulose, 2020 - Springer
Cellulose is lack of UV-blocking and antibacterial properties, which have limited its
application. In this work, the nanoscale lignin with high content of hydroxyl groups and small …

Symbiotic bacteria direct expression of an intestinal bactericidal lectin

HL Cash, CV Whitham, CL Behrendt, LV Hooper - Science, 2006 - science.org
The mammalian intestine harbors complex societies of beneficial bacteria that are
maintained in the lumen with minimal penetration of mucosal surfaces. Microbial …

[HTML][HTML] Neutrophils in innate host defense against Staphylococcus aureus infections

KM Rigby, FR DeLeo - Seminars in immunopathology, 2012 - Springer
Staphylococcus aureus has been an important human pathogen throughout history and is
currently a leading cause of bacterial infections worldwide. S. aureus has the unique ability …

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

M Li, D Chen, A Shiloh, J Luo, AY Nikolaev, J Qin… - Nature, 2002 - nature.com
The p53 tumour suppressor is a short-lived protein that is maintained at low levels in normal
cells by Mdm2-mediated ubiquitination and subsequent proteolysis,,. Stabilization of p53 is …

Peptidoglycan recognition proteins: modulators of the microbiome and inflammation

J Royet, D Gupta, R Dziarski - Nature Reviews Immunology, 2011 - nature.com
All animals, including humans, live in symbiotic association with microorganisms. The
immune system accommodates host colonization by the microbiota, maintains microbiota …

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

T Michel, JM Reichhart, JA Hoffmann, J Royet - Nature, 2001 - nature.com
Microbial infection activates two distinct intracellular signalling cascades in the immune-
responsive fat body of Drosophila,. Gram-positive bacteria and fungi predominantly induce …

The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein

M Gottar, V Gobert, T Michel, M Belvin, G Duyk… - Nature, 2002 - nature.com
The antimicrobial defence of Drosophila relies largely on the challenge-induced synthesis of
an array of potent antimicrobial peptides by the fat body,. The defence against Gram-positive …

Recognition of Staphylococcus aureus by the Innate Immune System

B Fournier, DJ Philpott - Clinical microbiology reviews, 2005 - Am Soc Microbiol
The gram-positive bacterium Staphylococcus aureus is a major pathogen responsible for a
variety of diseases ranging from minor skin infections to life-threatening conditions such as …