Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Ischemic heart disease and heart failure: role of coronary ion channels

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Heart failure is a complex syndrome responsible for high rates of death and hospitalization.
Ischemic heart disease is one of the most frequent causes of heart failure and it is normally …

Triggers for atrial fibrillation: the role of anxiety

P Severino, MV Mariani, A Maraone… - Cardiology research …, 2019 - Wiley Online Library
Atrial fibrillation (AF) is the most widely recognized arrhythmia. Systemic arterial
hypertension, diabetes, obesity, heart failure, and valvular heart diseases are major risk …

Prevention of cardiovascular disease: screening for magnesium deficiency

P Severino, L Netti, MV Mariani… - Cardiology research …, 2019 - Wiley Online Library
Magnesium is an essential mineral naturally present in the human body, where it acts as
cofactor in several enzymatic reactions. Magnesium is a key cardiovascular regulator, which …

Myocardial ischemia and diabetes mellitus: role of oxidative stress in the connection between cardiac metabolism and coronary blood flow

P Severino, A D'Amato, L Netti, M Pucci… - Journal of diabetes …, 2019 - Wiley Online Library
Ischemic heart disease (IHD) has several risk factors, among which diabetes mellitus
represents one of the most important. In diabetic patients, the pathophysiology of myocardial …

Advanced heart failure and end-stage heart failure: does a difference exist

P Severino, PJ Mather, M Pucci, A D'Amato… - Diagnostics, 2019 - mdpi.com
Advanced heart failure (AdHF) represents a challenging aspect of heart failure patients.
Because of worsening clinical symptoms, high rates of re-hospitalization and mortality, AdHF …

Heart failure pharmacological management: gaps and current perspectives

P Severino, A D'Amato, S Prosperi, V Myftari… - Journal of clinical …, 2023 - mdpi.com
Proper therapeutic management of patients with heart failure (HF) is a major challenge for
cardiologists. Current guidelines indicate to start therapy with angiotensin converting …

Structural and myocardial dysfunction in heart failure beyond ejection fraction

P Severino, V Maestrini, MV Mariani, LI Birtolo… - Heart failure …, 2020 - Springer
Heart failure is a multifaceted syndrome addressing for a high rate of death among the
general population. The common approach to this disease has been always based on the …

Do the current guidelines for heart failure diagnosis and treatment fit with clinical complexity?

P Severino, A D'Amato, S Prosperi, A Dei Cas… - Journal of Clinical …, 2022 - mdpi.com
Heart failure (HF) is a clinical syndrome defined by specific symptoms and signs due to
structural and/or functional heart abnormalities, which lead to inadequate cardiac output …

[PDF][PDF] 达格列净治疗心力衰竭疗效和安全性的Meta 分析

王喆, 魏芳, 陈海燕, 姜埃利 - 临床心血管病杂志, 2021 - lcxxg.whuhzzs.com
目的: 达格列净属于钠-葡萄糖协同转运蛋白2 (SGLT-2) 抑制剂. 本研究评价达格列净治疗心力
衰竭的疗效和安全性. 方法: 根据协同检索策略, 检索Medline, Embase, 中文万方数据库, CNKI …