[HTML][HTML] Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs
C Wang, H Lin - Genome Biology, 2021 - Springer
PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known
for their function in silencing transposons and germline development by partnering with …
for their function in silencing transposons and germline development by partnering with …
Long noncoding RNAs as new architects in cancer epigenetics, prognostic biomarkers, and potential therapeutic targets
D Meseure, K Drak Alsibai, A Nicolas… - BioMed research …, 2015 - Wiley Online Library
Recent advances in genome‐wide analysis have revealed that 66% of the genome is
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …
actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences …
[HTML][HTML] The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster
CL Webster, FM Waldron, S Robertson, D Crowson… - PLoS …, 2015 - journals.plos.org
Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …
Panoramix enforces piRNA-dependent cotranscriptional silencing
The Piwi-interacting RNA (piRNA) pathway is a small RNA–based innate immune system
that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear …
that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear …
The piRNA pathway is essential for generating functional oocytes in golden hamsters
H Zhang, F Zhang, Q Chen, M Li, X Lv, Y Xiao… - Nature cell …, 2021 - nature.com
Piwi-interacting RNAs (piRNAs) are predominantly expressed in germ cells and function in
gametogenesis in various species. However, Piwi-deficient female mice are fertile and …
gametogenesis in various species. However, Piwi-deficient female mice are fertile and …
Interactions between short and long noncoding RNAs
I Ulitsky - FEBS letters, 2018 - Wiley Online Library
It is now evident that noncoding RNAs play key roles in regulatory networks determining cell
fate and behavior, in a myriad of different conditions, and across all species. Among these …
fate and behavior, in a myriad of different conditions, and across all species. Among these …
Unique transposon landscapes are pervasive across Drosophila melanogaster genomes
To understand how transposon landscapes (TLs) vary across animal genomes, we describe
a new method called the Transposon Insertion and Depletion AnaLyzer (TIDAL) and a …
a new method called the Transposon Insertion and Depletion AnaLyzer (TIDAL) and a …
[HTML][HTML] Sex and the TEs: transposable elements in sexual development and function in animals
Transposable elements are endogenous DNA sequences able to integrate into and multiply
within genomes. They constitute a major source of genetic innovations, as they can not only …
within genomes. They constitute a major source of genetic innovations, as they can not only …
The capacity of target silencing by Drosophila PIWI and piRNAs
C Post, JP Clark, YA Sytnikova, GW Chirn, NC Lau - Rna, 2014 - rnajournal.cshlp.org
Although Piwi proteins and Piwi-interacting RNAs (piRNAs) genetically repress
transposable elements (TEs), it is unclear how the highly diverse piRNA populations direct …
transposable elements (TEs), it is unclear how the highly diverse piRNA populations direct …
[HTML][HTML] PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
D Li, DH Taylor, JC van Wolfswinkel - Cell reports, 2021 - cell.com
PIWI proteins are known as mediators of transposon silencing in animal germlines but are
also found in adult pluripotent stem cells of highly regenerative animals, where they are …
also found in adult pluripotent stem cells of highly regenerative animals, where they are …