Neuronal cytotoxic edema is the morphological correlate of the near-complete neuronal
battery breakdown called spreading depolarization, or conversely, spreading depolarization …

Background and Purpose Migraine is a complex neurovascular disorder whose triggers are
not entirely understood. Endothelial dysfunction might play a role in migraine, and there …

Migraine afflicts more than one billion individuals worldwide and is a leading cause of years
lived with disability. In about a third of individuals with migraine aura occur in relation to …

Background Although the involvement of calcitonin gene-related peptide (CGRP) in
migraines is well-established, its specific role in investigating the aura phase, which often …

In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …

Migraine, the third most common disease worldwide, is a well-known independent risk factor
for subclinical focal deep white matter lesions (WMLs), even in young and otherwise healthy …

Background Calcitonin gene-related peptide is recognized as a key player in migraine, yet
the mechanisms and sites of calcitonin gene-related peptide action remain unknown. The …

Introduction: This review aims to model migraine nociception. Methods: Personal experience
and litterature. Results: Genetic and environmental factors in combination decide whether a …

Introduction It has not been established if migraine headache and migraine aura share
common pathophysiological mechanisms. Sildenafil, a phosphodiesterase-5 inhibitor …

Enhanced activity of the glutamatergic system has been linked to migraine pathophysiology.
The present study aimed to assess the involvement of the glutamatergic system in the onset …