The applications of functionalized DNA nanostructures in bioimaging and cancer therapy
Deoxyribonucleic acid (DNA) is a molecular carrier of genetic information that can be
fabricated into functional nanomaterials in biochemistry and engineering fields. Those DNA …
fabricated into functional nanomaterials in biochemistry and engineering fields. Those DNA …
A proton‐activatable DNA‐based nanosystem enables co‐delivery of CRISPR/Cas9 and dnazyme for combined gene therapy
F Li, N Song, Y Dong, S Li, L Li, Y Liu… - Angewandte Chemie …, 2022 - Wiley Online Library
CRISPR/Cas9 is emerging as a platform for gene therapeutics, and the treatment efficiency
is expected to be enhanced by combination with other therapeutic agents. Herein, we report …
is expected to be enhanced by combination with other therapeutic agents. Herein, we report …
A dissipative pathway for the structural evolution of DNA fibres
Biochemical networks interconnect, grow and evolve to express new properties as different
chemical pathways are selected during a continuous cycle of energy consumption and …
chemical pathways are selected during a continuous cycle of energy consumption and …
Advances and new opportunities in the rheology of physically and chemically reversible polymers
S Wu, Q Chen - Macromolecules, 2021 - ACS Publications
The advances in understanding the dynamics of both the physically and chemically
reversible networks are summarized from a rheological perspective. The focus is placed on …
reversible networks are summarized from a rheological perspective. The focus is placed on …
Cascade dynamic assembly/disassembly of DNA nanoframework enabling the controlled delivery of CRISPR-Cas9 system
N Song, Y Chu, S Li, Y Dong, X Fan, J Tang, Y Guo… - Science …, 2023 - science.org
CRISPR-Cas9 has been explored as a therapeutic agent for down-regulating target genes;
the controlled delivery of Cas9 ribonucleoprotein (RNP) is essential for therapeutic efficacy …
the controlled delivery of Cas9 ribonucleoprotein (RNP) is essential for therapeutic efficacy …
Dissipative gated and cascaded DNA networks
Nucleic acid based, out-of-equilibrium, dissipative networks driven by nucleic acid fuels
coupled to the nicking enzyme, Nt. BbvCI, are presented. One set of experiments includes a …
coupled to the nicking enzyme, Nt. BbvCI, are presented. One set of experiments includes a …
Reversible diffusionless phase transitions in 3D nanoparticle superlattices
Nanocomposite tectons (NCTs), polymer brush-grafted nanoparticles that use
supramolecular interactions to drive their assembly, form ordered nanoparticle superlattices …
supramolecular interactions to drive their assembly, form ordered nanoparticle superlattices …
Flash synthesis of DNA hydrogel via supramacromolecular assembly of DNA chains and upconversion nanoparticles for cell engineering
J Tang, J Ou, C Zhu, C Yao… - Advanced Functional …, 2022 - Wiley Online Library
Deoxyribonucleic acid (DNA) hydrogel has been synthesized generally via the molecular
interaction of either DNA base‐pairing, covalent bonding, or physical entanglement. To …
interaction of either DNA base‐pairing, covalent bonding, or physical entanglement. To …
Amp aptamer programs DNA tile cohesion without canonical base pairing
Z Zhang, J Jin, VE Paluzzi, Z Jin, Y Wen… - Journal of the …, 2023 - ACS Publications
Tile-based DNA self-assembly provides a versatile approach for the construction of a wide
range of nanostructures for various applications such as nanomedicine and advanced …
range of nanostructures for various applications such as nanomedicine and advanced …