Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice

T Celhar, X Li, Y Zhao, HC Tay, A Lee, HH Liew… - Stem Cell Research & …, 2024 - Springer
Background Transplantation of CD34+ hematopoietic stem and progenitor cells (HSPC) into
immunodeficient mice is an established method to generate humanized mice harbouring a …

Prenatal Interventions for the Treatment of Congenital Disorders

K Singh - Regenerative Medicine: Emerging Techniques to …, 2023 - Springer
Congenital genetic defects are the leading cause of morbidity and mortality. With progress in
diagnostic methods, many of these diseases can be diagnosed prenatally. Prenatal …

[PDF][PDF] Elucidating Cell Fate Regulation of the Bone Marrow Vascular Niche Through Development of Engineered Extracellular Matrices

A Pagnani - 2023 - yorkspace.library.yorku.ca
Haematopoietic stem and progenitor cells (HSPCs) are crucial to the curative treatment of a
variety of leukaemias and autoimmune diseases. However, their rapid differentiation and …

Identification and characterization of primitive fetal hematopoietic cells

M MacAldaz - 2022 - open.library.ubc.ca
Identification of phenotypes of human hematopoietic cells that display long-term mature cell
outputs in vitro and repopulating capability in immunodeficient mice has been important to …