The drug delivery system enables the release of the active pharmaceutical ingredient to
achieve a desired therapeutic response. Conventional drug delivery systems (tablets …

Ibuprofen and acetaminophen as two anti-fever agents have been widely used in human.
Due to lack of full understanding, this work firstly summarized their occurrence and fate in …

The objective of this study was to develop a new approach for fabrication of zero order
release of active pharmaceutical ingredients (APIs) using hot-melt extrusion (HME) and 3D …

Abstract The Biopharmaceutics Classification System (BCS) categorizes drugs into one of
four biopharmaceutical classes according to their water solubility and membrane …

The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Two,
Uncompressed Solid Products is an authoritative and practical guide to the art and science …

Literature data are reviewed regarding the scientific advisability of allowing a waiver of in
vivo bioequivalence (BE) testing for the approval of immediate release (IR) solid oral dosage …

Paracetamol printlets were prepared via hot-melt extrusion process and fused deposition
modelling, using two types of backbone polymers. Polycaprolactone (PCL) and …

Literature and new experimental data relevant to the decision to allow a waiver of in vivo
bioequivalence (BE) testing for the approval of immediate release (IR) solid oral dosage …

To enable more precise prediction of oral drug absorption, an existing physiologically based
absorption model was revised. The revised model reflects detailed knowledge of human …

The hydrochlorides of the 1: 3 aluminum: norfloxacin and aluminum: ciprofloxacin
complexes were characterized according to the Biopharmaceutics Classification System …