Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an
autosomal dominant pattern, is continuing to raise great interest for endocrinology …

Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's
syndrome, including debilitating morbidities and increased mortality. Genetic and molecular …

Introduction With the goal of generate uniform criteria among centers dealing with pituitary
tumors and to enhance patient care, the Pituitary Society decided to generate criteria for …

Prevalence and incidence of prolactinomas are approximately 50 per 100,000 and 3–5 new
cases/100,000/year. The pathophysiological mechanism of hyperprolactinemia-induced …

Context: Data on the incidence of pituitary adenomas (PAs) are scant and outdated. A
population-based regional cohort with thorough case identification was used to evaluate the …

Dopamine agonists are usually very effective in the treatment of prolactinomas.
Nonetheless, a subset of individuals does not respond satisfactorily to these agents, and this …

Epidemiological data is important to correctly quantify the extent of disease and needed
health care resources. The aim of the study was to establish the prevalence and incidence of …

Context: Although pituitary tumors are common, pituitary carcinoma is very rare and is only
diagnosed when pituitary tumor noncontiguous with the sellar region is demonstrated …

Recently, a number of novel genetic alterations have been identified that predispose
individuals to pituitary adenomas. Clinically relevant pituitary adenomas are relatively …

Pituitary carcinoma is an aggressive tumor characterized by metastatic spread beyond the
sellar region. Symptoms can be debilitating due to hormonal excess and survival is poor …