▪ Abstract The female sex steroid hormones 17β-estradiol and progesterone mediate their
biological effects on development, differentiation, and maintenance of reproductive tract and …

BACKGROUND The steroid hormone progesterone is indispensable for mammalian
procreation by controlling key female reproductive events that range from ovulation to …

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to
provide the historical context to current research, and most importantly as an aid for …

The process and timing of human parturition involves a complex hormonal dialogue
between maternal and fetal systems that transforms the uterine muscle into the laboring …

The precise temporal control of uterine contractility is essential for the success of pregnancy.
For most of pregnancy, progesterone acting through genomic and non-genomic …

In preparation for delivery, the uterus transitions from actively maintaining quiescence during
pregnancy to an active parturient state. This transition occurs as a result of the accumulation …

Prostaglandins, produced from membrane phospholipids by the action of phospholipase A2,
cyclooxygenase, and specific prostaglandin synthases, are important regulators of ovulation …

Classically, progesterone has been thought to act only through the well-known genomic
pathway involving hormone binding to nuclear receptors (nPR) and subsequent modulation …

Progesterone is a major factor maintaining uterine quiescence throughout pregnancy. In
most species, peripheral progesterone levels decline before initiation of labor, and …

Uterine leiomyomas (ULs) are the most common benign smooth muscle cell steroid-
dependent tumors that occur in women of reproductive age. Progesterone (P4) is a major …