When helper T (TH) cell polarization was initially described three decades ago, the TH cell
universe grew dramatically. New subsets were described based on their expression of few …

SLE is characterised by an activation of the interferon (IFN) system, which leads to an
increased expression of IFN-regulated genes. The reasons behind the IFN signature in SLE …

The interferons (IFNs) are a family of cytokines that protect against disease by direct effects
on target cells and by activating immune responses. The production and actions of IFNs are …

Abstract Interferome v2. 0 (http://interferome. its. monash. edu. au/interferome/) is an update
of an earlier version of the Interferome DB published in the 2009 NAR database edition …

Interferons (IFNs) induce the expression of hundreds of genes as part of an elaborate
antimicrobial programme designed to combat infection in all nucleated cells—a process …

Abstract Background and aim Interferons (IFNs) are considered to be key molecules in the
pathogenesis of systemic lupus erythematosus (SLE). We measured levels of type I, II and III …

The majority of patients with systemic lupus erythematosus (SLE) have high expression of
type I IFN-stimulated genes. Mitochondrial abnormalities have also been reported, but the …

Both type I and II interferons (IFNs) have been implicated in the pathogenesis of Sjogren's
syndrome (SS). We aimed to explore the contribution of type I and II IFN signatures in the …

The term interferon describes a family of proteins consisting of three major types (I, II, III)
which differ in their primary protein sequences, cognate receptors, genetic loci, and cell …

The interferon signature in autoimmune diseases : Current Opinion in Rheumatology The
interferon signature in autoimmune diseases : Current Opinion in Rheumatology Log in or …