Mammalian cell membranes are composed of a complex array of glycerophospholipids and
sphingolipids that vary in head-group and acyl-chain composition. In a given cell type …

Abstract Differential Scanning Calorimetry (DSC) is a highly sensitive technique to study the
thermotropic properties of many different biological macromolecules and extracts. Since its …

The effects of cholesterol on membrane bending modulus KC, membrane thickness D HH,
the partial and apparent areas of cholesterol and lipid, and the order parameter S xray are …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

We have determined the molecular structures of commonly used phosphatidylglycerols
(PGs) in the commonly accepted biologically relevant fluid phase. This was done by …

Our understanding of the role of cholesterol in biological membranes requires a detailed
knowledge of the forces which mediate cholesterol-lipid interactions and of the lateral …

This review deals with the effect of variations in phospholipid and sterol structure on the
nature and magnitude of lipid-sterol interactions in lipid bilayer model membranes. The first …

A fluorescence-quenching method has been used to assess the potential formation of
segregated liquid-ordered domains in lipid bilayers combining cholesterol with mixtures of …

We synthesized a family of sterol-modified glycerophospholipids (SML) in which the sn-1 or
sn-2 position is covalently attached to cholesterol and the alternative position contains an …

Liposomes are well recognised for their ability to improve the delivery of a range of drugs.
More commonly they are applied for the delivery of water-soluble drugs, but given their …