Current evidence in SARS-CoV-2 mRNA vaccines and post-vaccination adverse reports: knowns and unknowns

DS Mouliou, E Dardiotis - Diagnostics, 2022 - mdpi.com
The novel mRNA vaccinations against COVID-19 are gaining worldwide attention for their
potential efficacy, as well as for the diagnosis of some post-vaccination-reported adverse …

Multiple sclerosis and SARS-CoV-2: has the interplay started?

G Bellucci, V Rinaldi, MC Buscarinu, R Reniè… - Frontiers in …, 2021 - frontiersin.org
Current knowledge on Multiple Sclerosis (MS) etiopathogenesis encompasses complex
interactions between the host's genetic background and several environmental factors that …

[HTML][HTML] Long COVID or post COVID-19 syndrome

J Lechner-Scott, M Levy, C Hawkes, A Yeh… - Multiple sclerosis and …, 2021 - ncbi.nlm.nih.gov
SARS-COV-2 is now recognized to be responsible not only for a lung condition but a multi-
organ syndrome (Ramakrishnan et al., 2021). After the initial acute infection, like many other …

Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment

J Gruchot, I Lewen, M Dietrich… - Proceedings of the …, 2023 - National Acad Sciences
The human endogenous retrovirus type W (HERV-W) has been identified and repeatedly
confirmed as human-specific pathogenic entity affecting many cell types in multiple sclerosis …

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for …

ET Baldwin, M Götte, EP Tchesnokov… - Proceedings of the …, 2022 - National Acad Sciences
Human endogenous retroviruses (HERVs) comprise nearly 8% of the human genome and
are derived from ancient integrations of retroviruses into the germline. The biology of HERVs …

p53/NF-kB balance in SARS-CoV-2 infection: From OMICs, genomics and pharmacogenomics insights to tailored therapeutic perspectives (COVIDomics)

D Milani, L Caruso, E Zauli, AM Al Owaifeer… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection affects different organs and tissues, including the upper and lower
airways, the lung, the gut, the olfactory system and the eye, which may represent one of the …

Human endogenous retrovirus K in the respiratory tract is associated with COVID-19 physiopathology

JR Temerozo, N Fintelman-Rodrigues, MC Dos Santos… - Microbiome, 2022 - Springer
Background Critically ill 2019 coronavirus disease (COVID-19) patients under invasive
mechanical ventilation (IMV) are 10 to 40 times more likely to die than the general …

COVID-19 in children: expressions of type I/II/III interferons, TRIM28, SETDB1, and endogenous retroviruses in mild and severe cases

PA Tovo, S Garazzino, V Dapra, G Pruccoli… - International journal of …, 2021 - mdpi.com
Children with the new coronavirus disease 2019 (COVID-19) have milder symptoms and a
better prognosis than adult patients. Several investigations assessed type I, II, and III …

Patients with psychosis spectrum disorders hospitalized during the COVID-19 pandemic unravel overlooked SARS-CoV-2 past infection clustering with HERV-W ENV …

R Tamouza, U Meyer, A Lucas, JR Richard… - Translational …, 2023 - nature.com
Epidemiology has repeatedly associated certain infections with a risk of further developing
psychiatric diseases. Such infections can activate retro-transposable genetic elements …

[HTML][HTML] SARS-CoV-2 infection mediates differential expression of human endogenous retroviruses and long interspersed nuclear elements

JL Marston, M Greenig, M Singh, ML Bendall… - JCI insight, 2021 - ncbi.nlm.nih.gov
SARS-CoV-2 promotes an imbalanced host response that underlies the development and
severity of COVID-19. Infections with viruses are known to modulate transposable elements …