An optimal early life environment is crucial for ensuring ideal neurodevelopmental
outcomes. Brain development consists of a finely tuned series of spatially and temporally …

Background Despite the widespread use of antenatal corticosteroids to prevent respiratory
distress syndrome in preterm infants, there is currently no consensus as to the type of …

A course of antenatal corticosteroids given within the seven days prior to preterm birth
reduces perinatal and neonatal death and respiratory distress syndrome.[Grade A] For …

Preterm birth is associated with a high risk of morbidity and mortality including brain damage
and cerebral palsy. The development of brain injury in the preterm infant may be influenced …

Importance Interventions to reduce severe brain injury risk are the prime focus in neonatal
clinical trials. Objective To evaluate multiple perinatal interventions across clinical settings …

The complications of prematurity are the leading cause of neonatal mortality worldwide, with
the highest burden in the low-and middle-income countries of South Asia and Sub-Saharan …

We review the history of antenatal corticosteroid therapy (ACS) and present recent
experimental data to demonstrate that this, one of the pillars of perinatal care, has been …

Abstract Summary of recommendations Corticosteroids should be administered to women at
a gestational age between 24+ 0 and 33+ 6 weeks, when preterm birth is anticipated in the …

For women with a singleton or a multiple pregnancy in situations where active neonatal care
is appropriate, and for whom preterm birth is anticipated between 24 and 34 weeks of …

Objective This study aimed to evaluate the comparative clinical effectiveness and safety of
dexamethasone vs betamethasone for preterm birth. Data Sources The sources searched …