Lutetium-177 therapeutic radiopharmaceuticals: linking chemistry, radiochemistry, and practical applications
S Banerjee, MRA Pillai, FF Knapp - Chemical reviews, 2015 - ACS Publications
Interest in the use of radionuclides for treatment of various diseases has a long history and
parallels the isolation of radium by Marie and Pierre Curie in the early part of the 20th …
parallels the isolation of radium by Marie and Pierre Curie in the early part of the 20th …
Peptide receptor radionuclide therapy: an overview
Peptide receptor radionuclide therapy (PRRT) is a site-directed targeted therapeutic strategy
that specifically uses radiolabeled peptides as biological targeting vectors designed to …
that specifically uses radiolabeled peptides as biological targeting vectors designed to …
Radiotheranostics with radiolanthanides: Design, development strategies, and medical applications
K Mishiro, H Hanaoka, A Yamaguchi… - Coordination chemistry …, 2019 - Elsevier
Abstract “Radiotheranostics” is a term used in nuclear medicine to refer to the use of
radioisotope (RI)-labeled agents to perform simultaneous imaging and therapy of a target …
radioisotope (RI)-labeled agents to perform simultaneous imaging and therapy of a target …
[HTML][HTML] A review of advances in the last decade on targeted cancer therapy using 177Lu: Focusing on 177Lu produced by the direct neutron activation route
R Chakravarty, S Chakraborty - American Journal of Nuclear …, 2021 - ncbi.nlm.nih.gov
Abstract Lutetium-177 [T½= 6.76 d; E β (max)= 0.497 MeV; maximum tissue range~ 2.5 mm;
208 keV γ-ray] is one of the most important theranostic radioisotope used for the …
208 keV γ-ray] is one of the most important theranostic radioisotope used for the …
68Ga-DOTA-RGD2 positron emission tomography/computed tomography in radioiodine refractory thyroid cancer: prospective comparison of diagnostic accuracy with …
Background: Radioiodine therapy (131I) forms a principal cornerstone in the management of
differentiated thyroid cancer. Radioiodine-refractory differentiated thyroid cancer (RAIR …
differentiated thyroid cancer. Radioiodine-refractory differentiated thyroid cancer (RAIR …
Theranostic options for radioiodine-refractory differentiated thyroid carcinoma: recent advances, challenges, and road ahead
S Satapathy, C Bal - Frontiers in Endocrinology, 2022 - frontiersin.org
Radioiodine-refractory differentiated thyroid cancer (RAIR-DTC), though uncommon,
presents a considerable therapeutic challenge with poor long-term outcomes. Currently …
presents a considerable therapeutic challenge with poor long-term outcomes. Currently …
A systematic study on the utility of CHX-A''-DTPA-NCS and NOTA-NCS as bifunctional chelators for 177Lu radiopharmaceuticals
U Pandey, N Gamre, SP Lohar, A Dash - Applied Radiation and Isotopes, 2017 - Elsevier
This paper describes the evaluation of [(R)-2-Amino-3-(4-isothiocyanatophenyl) propyl]-
trans-(S, S)-cyclohexane-1, 2-diamine-pentaacetic acid (CHX-A''-DTPA-NCS) and 2-S-(4 …
trans-(S, S)-cyclohexane-1, 2-diamine-pentaacetic acid (CHX-A''-DTPA-NCS) and 2-S-(4 …
Electrochemical separation of 132/135La theranostic pair from proton irradiated Ba target
R Chakravarty, S Patra, KC Jagadeesan… - Separation and …, 2022 - Elsevier
Abstract Lanthanum-132/135 is an emerging theranostic pair of radiometals that might find
widespread application in nuclear medicine. The present study describes the production of …
widespread application in nuclear medicine. The present study describes the production of …
Preparation and preclinical evaluation of 66Ga-DOTA-E (c (RGDfK)) 2 as a potential theranostic radiopharmaceutical
V Lopez-Rodriguez, RE Gaspar-Carcamo… - Nuclear Medicine and …, 2015 - Elsevier
Introduction Integrin α v β 3 plays an important role in angiogenesis and is over-expressed
in tumoral endothelial cells and some other tumor cells. RGD (Arg-Gly-Asn) peptides labeled …
in tumoral endothelial cells and some other tumor cells. RGD (Arg-Gly-Asn) peptides labeled …
A systematic evaluation of the potential of PCTA-NCS ligand as a bifunctional chelating agent for design of 177Lu radiopharmaceuticals
U Pandey, N Gamre, Y Kumar, P Shetty… - … of Radioanalytical and …, 2016 - Springer
This paper explores the utility of para isothiocyanato benzyl 3, 6, 9, 15-tetraazabicyclo [9.3.
1] pentadeca-1 (15), 11, 13-triene-3, 6, 9-triacetic acid (PCTA-NCS) as a bifunctional …
1] pentadeca-1 (15), 11, 13-triene-3, 6, 9-triacetic acid (PCTA-NCS) as a bifunctional …