Ancestral environmental exposures such as toxicants, abnormal nutrition or stress can
promote the epigenetic transgenerational inheritance of disease and phenotypic variation …

Recent research using Drosophila melanogaster has seen a resurgence in studies of
metabolism and physiology. This review focuses on major methods used to conduct this …

Interest in the field of epigenetics has increased rapidly over the last decade, with the term
becoming more identifiable in biomedical research, scientific fields outside of the molecular …

The global rise in obesity has revitalized a search for genetic and epigenetic factors
underlying the disease. We present a Drosophila model of paternal-diet-induced …

Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …

The prevalence of obesity and associated diseases has reached pandemic levels. Obesity is
often associated with overnutrition and a sedentary lifestyle, but clearly other factors also …

Environmental exposures such as toxicants, nutrition and stress have been shown to
promote the epigenetic transgenerational inheritance of disease susceptibility. Endocrine …

Epigenetic changes are caused by biochemical regulators of gene expression that can be
transferred across generations or through cell division. Epigenetic modifications can arise …

Environmental factors can induce epigenetic alterations in the germ cells that can potentially
be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic …

It has become clear that early life (including in utero exposures) is a key window of
vulnerability during which environmental exposures can alter developmental trajectories …