COVID-19 therapeutics: Challenges and directions for the future
PC Robinson, DFL Liew, HL Tanner… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of SARS-CoV-2 triggering the COVID-19 pandemic ranks as arguably the
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …
[HTML][HTML] COVID-19 outcomes in patients undergoing B cell depletion therapy and those with humoral immunodeficiency states: a scoping review
Background: The role of humoral immunity has been well established in reducing infection
risk and facilitating viral clearance in patients with COVID-19. However, the relationship …
risk and facilitating viral clearance in patients with COVID-19. However, the relationship …
Effect of immunosuppression on the immunogenicity of mRNA vaccines to SARS-CoV-2: a prospective cohort study
Background: Patients with chronic inflammatory disease (CID) treated with
immunosuppressive medications have increased risk for severe COVID-19. Although mRNA …
immunosuppressive medications have increased risk for severe COVID-19. Although mRNA …
COVID-19 vaccine effectiveness against omicron (B. 1.1. 529) variant infection and hospitalisation in patients taking immunosuppressive medications: a retrospective …
Background There is a scarcity of research regarding the effectiveness of the mRNA-1273
(Moderna) and BNT162b2 (Pfizer-BioNTech) COVID-19 vaccines in patients taking …
(Moderna) and BNT162b2 (Pfizer-BioNTech) COVID-19 vaccines in patients taking …
Absence of humoral response after two-dose SARS-CoV-2 messenger RNA vaccination in patients with rheumatic and musculoskeletal diseases: a case series
Background: Patients with rheumatic and musculoskeletal diseases (RMDs) are at
increased risk for SARS-CoV-2 infection because of both the immunomodulatory effects of …
increased risk for SARS-CoV-2 infection because of both the immunomodulatory effects of …
Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273
NJM Verstegen, RR Hagen, J van den Dijssel… - Elife, 2022 - elifesciences.org
Background: Patients affected by different types of autoimmune diseases, including common
conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …
conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …
COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis
Objectives The objectives of this study were to investigate the incidence of COVID-19
hospitalization in unvaccinated and vaccinated patients with RA compared with matched …
hospitalization in unvaccinated and vaccinated patients with RA compared with matched …
COVID-19 hospitalizations, intensive care unit stays, ventilation, and death among patients with immune-mediated inflammatory diseases compared to controls
Objective To investigate coronavirus disease 2019 (COVID-19) hospitalization risk in
patients with immune-mediated inflammatory diseases (IMIDs) compared with matched non …
patients with immune-mediated inflammatory diseases (IMIDs) compared with matched non …
Efficacy of COVID-19 mRNA vaccination in patients with autoimmune disorders: humoral and cellular immune response
F Filippini, M Giacomelli, C Bazzani, M Fredi… - BMC medicine, 2023 - Springer
Background The impact of immunosuppressive therapies on the efficacy of vaccines to
SARS-CoV-2 is not completely clarified. We analyzed humoral and T cell-mediated …
SARS-CoV-2 is not completely clarified. We analyzed humoral and T cell-mediated …
[HTML][HTML] High T-cell response rate after COVID-19 vaccination in belimumab and rituximab recipients
M Fabris, G De Marchi, R Domenis, F Caponnetto… - Journal of …, 2022 - Elsevier
Objective To evaluate B-cell-and T-cell-mediated immune response to SARS-CoV-2 mRNA
vaccination in patients with complex or rare systemic autoimmune diseases previously been …
vaccination in patients with complex or rare systemic autoimmune diseases previously been …