Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
E Schrezenmeier, T Dörner - Nature Reviews Rheumatology, 2020 - nature.com
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …
chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus …
COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression
D Zhou, SM Dai, Q Tong - Journal of Antimicrobial …, 2020 - academic.oup.com
A novel coronavirus disease (COVID-19), caused by infection with SARS-CoV-2, has swept
across 31 provinces in China and over 40 countries worldwide. The transition from first …
across 31 provinces in China and over 40 countries worldwide. The transition from first …
Management strategies and future directions for systemic lupus erythematosus in adults
L Durcan, T O'Dwyer, M Petri - The Lancet, 2019 - thelancet.com
Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of
self-tolerance and formation of nuclear autoantigens and immune complexes resulting in …
self-tolerance and formation of nuclear autoantigens and immune complexes resulting in …
Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge
A Dima, C Jurcut, F Chasset… - Therapeutic …, 2022 - journals.sagepub.com
The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …
the treatment of systemic lupus erythematosus (SLE). Herein, we reviewed the main HCQ …
The immunology of COVID-19: is immune modulation an option for treatment?
J Zhong, J Tang, C Ye, L Dong - The Lancet Rheumatology, 2020 - thelancet.com
In December, 2019, an outbreak of COVID-19 emerged in Wuhan, China and quickly spread
globally. As of May 7, 2020, there were 3 672 238 confirmed infections and 254 045 deaths …
globally. As of May 7, 2020, there were 3 672 238 confirmed infections and 254 045 deaths …
Treating systemic lupus erythematosus in the 21st century: new drugs and new perspectives on old drugs
G Ruiz-Irastorza, G Bertsias - Rheumatology, 2020 - academic.oup.com
Besides treating acute flares, the management of SLE should aim at preventing organ
damage accrual and drug-associated harms, improving health-related quality of life and …
damage accrual and drug-associated harms, improving health-related quality of life and …
COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease
R Fernandez-Ruiz, JL Paredes, TB Niewold - Translational Research, 2021 - Elsevier
As the world navigates the coronavirus disease 2019 (COVID-19) pandemic, there is a
growing need to assess its impact in patients with autoimmune rheumatic diseases, such as …
growing need to assess its impact in patients with autoimmune rheumatic diseases, such as …
The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment
J Listing, K Gerhold, A Zink - Rheumatology, 2013 - academic.oup.com
RA is known to be associated with an increased risk of serious infection. Even more than 50
years ago, observational studies showed a greater than 2-fold increased risk of serious …
years ago, observational studies showed a greater than 2-fold increased risk of serious …
The therapeutic landscape of rheumatoid arthritis: current state and future directions
S Shams, JM Martinez, JRD Dawson, J Flores… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …
emotional and socioeconomic consequences. Despite advances in targeted biologic and …
Infection risk in systemic lupus erythematosus patients: susceptibility factors and preventive strategies
A Danza, G Ruiz-Irastorza - Lupus, 2013 - journals.sagepub.com
Infection is one of the leading causes of morbidity and mortality in systemic lupus
erythematosus (SLE). Bacterial infections are most frequent, followed by viral and fungal …
erythematosus (SLE). Bacterial infections are most frequent, followed by viral and fungal …