Abstract Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin
(NGAL), is a secreted glycoprotein that belongs to a group of transporters of small lipophilic …

Along with microglia and monocyte-derived macrophages, macrophages in the perivascular
space, choroid plexus, and meninges are the principal effector cells in neuroinflammatory …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

Lipocalin 2 (Lcn2), an innate immune protein, has emerged as a critical iron regulatory
protein during physiological and inflammatory conditions. As a bacteriostatic factor, Lcn2 …

Astrocytes provide structural and functional support for neurons, as well as display
neurotoxic or neuroprotective phenotypes depending upon the presence of an immune or …

Sepsis is a prevalent health issue that can lead to central nervous system (CNS)
inflammation with long-term behavioral and cognitive alterations. Using unbiased proteomic …

Chronic itch is an intractable symptom of inflammatory skin diseases, such as atopic and
contact dermatitis,,. Recent studies have revealed neuronal pathways selective for itch …

Astrocytes play essential roles in development, homeostasis, injury, and repair of the central
nervous system (CNS). Their development is tightly regulated by distinct spatial and …

Abstract Lipocalin-2 (LCN2) is an acute-phase protein that, by binding to iron-loaded
siderophores, acts as a potent bacteriostatic agent in the iron-depletion strategy of the …

Abstract Lipocalin-2 (LCN2) is an acute phase protein with multiple functions that has
garnered a great deal of interest over the last decade. However, its precise role in the …