The pervasive role of the miR-181 family in development, neurodegeneration, and cancer

A Indrieri, S Carrella, P Carotenuto, S Banfi… - International journal of …, 2020 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …

Role of miR‑181a‑5p in cancer

J Li, J Shen, Y Zhao, F Du, M Li… - International …, 2023 - spandidos-publications.com
MicroRNAs (miRNAs) are non‑coding RNAs (ncRNAs) that can post‑transcriptionally
suppress targeted genes. Dysregulated miRNAs are associated with a variety of diseases …

A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization

W Liu, M Yu, F Chen, L Wang, C Ye, Q Chen… - Journal of …, 2021 - Springer
Background Many patients suffer from implant loosening after the implantation of titanium
alloy caused by immune response to the foreign bodies and this could inhibit the following …

Extracellular vesicle miRNAs promote the intestinal microenvironment by interacting with microbes in colitis

Q Shen, Z Huang, L Ma, J Yao, T Luo, Y Zhao… - Gut …, 2022 - Taylor & Francis
Inflammatory bowel disease (IBD) is a global disease with no cure. Disruption of the
microbial ecosystem is considered to be an important cause of IBD. Extracellular vesicles …

Double-edged sword role of miRNA-633 and miRNA-181 in human cancers

J Gupta, M Suliman, R Ali, R Margiana, A Hjazi… - … -Research and Practice, 2023 - Elsevier
Understanding the function and mode of operation of microRNAs (miRNAs) in cancer is of
growing interest. The short non-coding RNAs known as miRNAs, which target mRNA in …

The miR‐181 family: Wide‐ranging pathophysiological effects on cell fate and function

A Bell‐Hensley, S Das… - Journal of cellular …, 2023 - Wiley Online Library
MicroRNAs (miRNAs) are epigenetic regulators that can target and inhibit translation of
multiple mRNAs within a given cell type. As such, a number of different pathways and …

The functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapy

C Luan, Z Yang, B Chen - OncoTargets and therapy, 2015 - Taylor & Francis
MicroRNAs (miRNAs), a new class of noncoding RNAs, which can hybridize to target
messenger RNAs and regulate their expression posttranscriptionally, express differentially …

Exosomal miR-181a-5p reduce Mycoplasma gallisepticum (HS strain) infection in chicken by targeting PPM1B and activating the TLR2-mediated MyD88/NF-κB …

Y Sun, Y Wang, Y Zhao, M Zou, X Peng - Molecular Immunology, 2021 - Elsevier
Mycoplasma gallisepticum (MG) is one of the most important pathogens that causes chronic
respiratory disease (CRD) in chickens. Exosomes secreted from cells have been well …

miR‐181a/b therapy in lung cancer: reality or myth?

C Braicu, D Gulei, R Cojocneanu, L Raduly… - Molecular …, 2019 - Wiley Online Library
Despite substantial progress in oncology, lung cancer remains the number one malignancy
in terms of both incidence and mortality rates, and there thus remains an urgent need for …

Silencing of exosomal miR-181a reverses pediatric acute lymphocytic leukemia cell proliferation

S Haque, SR Vaiselbuh - Pharmaceuticals, 2020 - mdpi.com
Exosomes are cell-generated nano-vesicles found in most biological fluids. Major
components of their cargo are lipids, proteins, RNA, DNA, and non-coding RNAs. The …