Chagas disease: from discovery to a worldwide health problem
KCF Lidani, FA Andrade, L Bavia… - Frontiers in public …, 2019 - frontiersin.org
Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in
his honor, just over a century ago. He described the clinical aspects of the disease …
his honor, just over a century ago. He described the clinical aspects of the disease …
Chagas disease in the United States: a public health approach
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …
Randomized trial of benznidazole for chronic Chagas' cardiomyopathy
CA Morillo, JA Marin-Neto, A Avezum… - … England Journal of …, 2015 - Mass Medical Soc
Background The role of trypanocidal therapy in patients with established Chagas'
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
Chagas' disease
C Bern - New England Journal of Medicine, 2015 - Mass Medical Soc
Chagas’ Disease | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …
Chagas disease
JA Pérez-Molina, I Molina - The Lancet, 2018 - thelancet.com
Chagas disease is an anthropozoonosis from the American continent that has spread from
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …
II Consenso Brasileiro em doença de Chagas, 2015
JCP Dias, AN Ramos Jr, ED Gontijo… - … e Serviços de …, 2016 - SciELO Public Health
RESUMO A doença de Chagas é uma condição crônica negligenciada com elevada carga
de morbimortalidade e impacto dos pontos de vista psicológico, social e econômico …
de morbimortalidade e impacto dos pontos de vista psicológico, social e econômico …
Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled …
F Torrico, J Gascon, L Ortiz, C Alonso-Vega… - The Lancet Infectious …, 2018 - thelancet.com
Background Chagas disease is a major neglected vector-borne disease. In this study, we
investigated the safety and efficacy of three oral E1224 (a water-soluble ravuconazole …
investigated the safety and efficacy of three oral E1224 (a water-soluble ravuconazole …
[HTML][HTML] 2 nd Brazilian Consensus on Chagas Disease, 2015
JCP Dias, AN Ramos Jr, ED Gontijo… - Revista da Sociedade …, 2016 - SciELO Brasil
Chagas disease is a neglected chronic condition with a high burden of morbidity and
mortality. It has considerable psychological, social, and economic impacts. The disease …
mortality. It has considerable psychological, social, and economic impacts. The disease …
Benznidazole and Posaconazole in Eliminating Parasites in Asymptomatic T. Cruzi Carriers: The STOP-CHAGAS Trial
CA Morillo, H Waskin, S Sosa-Estani… - Journal of the American …, 2017 - jacc.org
Background: Benznidazole is recommended for treatment of Chagas infection. Effects of
combination therapy with benznidazole and posaconazole have not been tested in …
combination therapy with benznidazole and posaconazole have not been tested in …
Chagas disease drug discovery: toward a new era
E Chatelain - Journal of biomolecular screening, 2015 - journals.sagepub.com
American trypanosomiasis, or Chagas disease, is the result of infection by the Trypanosoma
cruzi parasite. Endemic in Latin America where it is the major cause of death from …
cruzi parasite. Endemic in Latin America where it is the major cause of death from …