The gene of transcriptional repressor GATA binding 1 (TRPS1), as an atypical GATA
transcription factor, has received considerable attention in a plethora of physiological and …

The development and repair of dentin are strictly regulated by hundreds of genes. Abnormal
dentin development is directly caused by gene mutations and dysregulation. Understanding …

The aim: To establish the features of the structural organization of enamel in various
anatomical areas of the tooth and determine their influence on the characteristics of the …

Bone mineralization is an orchestrated process by which mineral crystals are deposited by
osteoblasts; however, the detailed mechanisms remain to be elucidated. The presence of …

Serine protease inhibitor SerpinB2 is one of the most upregulated proteins following cellular
stress. This multifunctional serpin has been attributed a number of pleiotropic activities …

Dental caries is the most common chronic disease in children and adults worldwide. The
complex etiology of dental caries includes environmental factors as well as host genetics …

Cementum is the least studied of all mineralized tissues and little is known about
mechanisms regulating its formation. Therefore, the goal of this study was to provide new …

Tissue repair in adult mammals lacks the regenerative ability of many tissues in other adult
organisms like axolotl and newts. In this issue of Cell Stem Cell, Mascharak et al. use multi …

It has been discovered that Trichorhinophalangeal Syndrome-1 (TRPS1), a novel member of
the GATA transcription factor family, participates in both normal physiological processes and …

Trichorhinophalangeal syndrome type I (TRPS I; MIM 190350) is a rare autosomal dominant
disorder of congenital malformations due to variants of the gene TRPS1. We reported on an …