The role of silicon in drug discovery: a review

JL Panayides, DL Riley, F Hasenmaile… - RSC Medicinal …, 2024 - pubs.rsc.org
This review aims to highlight the role of silicon in drug discovery. Silicon and carbon are
often regarded as being similar with silicon located directly beneath carbon in the same …

Schiff Base of 3‐Aminopropylalkoxysilanes and 3‐Aminopropylsilatranes: Importance of Investigations and the Potential Applications

NV Vchislo, SN Adamovich… - Applied …, 2024 - Wiley Online Library
The escalating fascination with Schiff bases stems from their versatile applications in
medicine, pharmacology, biology, fine organic synthesis, and industrial processes. This …

New Functional Alkoxysilanes and Silatranes: Synthesis, Structure, Properties, and Possible Applications

SN Adamovich, AM Nalibayeva… - International Journal of …, 2023 - mdpi.com
The aza-Michael reaction of 3-aminopropyltriethoxysilane (1) and-silatrane (2) with acrylates
affords functionalized silyl-(3–8) and silatranyl-(9–14) mono-and diadducts with up to a 99 …

New 3-Aminopropylsilatrane Derivatives: Synthesis, Structure, Properties, and Biological Activity

SN Adamovich, IA Ushakov, EN Oborina… - International Journal of …, 2023 - mdpi.com
The biologically active compound 3-aminopropylsilatrane (a compound with a
pentacoordinated silicon atom) underwent an aza-Michael reaction with various acrylates …

3-Aminopropyltrietoxysilane and–Silatrane in the Michael Aza-Reaction with Acrylates. Synthesis, Structure, and Properties of Adducts

SN Adamovich, EN Oborina, MD Katerinich - Russian Journal of General …, 2023 - Springer
Aminopropyltriethoxysilane and-silatrane readily enter into the Michael aza reaction with
various acrylates. Depending on the ratio of the reagents, Michael mono-or diadducts …

От тетраэдрической координации атома кремния к тригонально-бипирамидальной в молекулах (органил) трифторсиланов

ЭА Зельбст, СН Адамович… - Химическая …, 2023 - chemsafety.ru
Аннотация Проведен анализ кристаллической структуры молекул (органил)
трифторсиланов, содержащих атом кремния в пентакоординированном состоянии …