[HTML][HTML] Chitosan: a potential biopolymer in drug delivery and biomedical applications
Chitosan, a biocompatible and biodegradable polysaccharide derived from chitin, has
surfaced as a material of promise for drug delivery and biomedical applications. Different …
surfaced as a material of promise for drug delivery and biomedical applications. Different …
[HTML][HTML] Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …
but the solubility parameter cannot compromise, and so different approaches are employed …
Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications
MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …
released by both animal and plant cells. These ubiquitous vesicles are involved in …
[HTML][HTML] Advances in drug delivery systems, challenges and future directions
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …
most diseases have created the need to specifically target the cells involved in the initiation …
[HTML][HTML] A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
Targeted protein degradation offers an alternative modality to classical inhibition and holds
the promise of addressing previously undruggable targets to provide novel therapeutic …
the promise of addressing previously undruggable targets to provide novel therapeutic …
RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract
Oral drug delivery of proteins is limited by the degradative environment of the
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …
Mucoadhesive carriers for oral drug delivery
Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …
administration and patients' compliance, over injectable, suppositories, ocular and nasal …
Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
[HTML][HTML] Buccal films: A review of therapeutic opportunities, formulations & relevant evaluation approaches
L Shipp, F Liu, L Kerai-Varsani, TC Okwuosa - Journal of Controlled …, 2022 - Elsevier
The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …
[HTML][HTML] Advancements in antimicrobial nanoscale materials and self-assembling systems
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …