Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

The major histocompatibility complex (MHC) is one of the most extensively studied regions
in the human genome because of the association of variants at this locus with autoimmune …

The major histocompatibility complex system is the most polymorphic gene cluster of the
mammal genome. In humans, this is a genomic locus known as the human leukocyte …

Autoimmune diseases (AIDs) are characterized by a multifactorial aetiology and a complex
genetic background, with the MHC region playing a major role. We genotyped for HLA …

The Major Histocompatibility Complex (MHC) makes the largest genetic contribution to
multiple sclerosis (MS) susceptibility, with 32 independent effects across the region …

Objective To identify the contribution of HLA-DRB1 alleles to susceptibility or resistance to
multiple sclerosis (MS) in Caucasians through a meta-analysis of non-family-based studies …

Self-identified Hispanic/Latino individuals living with multiple sclerosis (MS) in the
continental United States (US) are a diverse group that represents different cultural and …

Abstract Background The cause of Multiple Sclerosis (MS) remains poorly understood, but it
is widely believed to be an autoimmune disease occurring in genetically susceptible …

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system
(CNS), the clinical course of which varies considerably between patients. Genetic complexity …

Background and objective: The association of HLA‐DRB1* 15 with susceptibility to multiple
sclerosis (MS) has been consistently reported although its effect on the clinical phenotype is …