Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …

Bacteria live in environments that are subject to rapid changes in the availability of the
nutrients that are necessary to provide energy and biosynthetic intermediates for the …

The accessory sigma factor σB controls a general stress response that is thought to be
important for Staphylococcus aureus survival and may contribute to virulence. The strain of …

Although considered to be an extracellular pathogen, Staphylococcus aureus is able to
invade a variety of mammalian, non-professional phagocytes and can also survive …

The virulence of Staphylococcus aureus is essentially determined by cell wall associated
proteins and secreted toxins that are regulated and expressed according to growth phases …

Staphylococcus aureus is a major human pathogen that causes a range of infections from
acute invasive to chronic and difficult-to-treat. Infection strategies associated with persisting …

One of the strongest and most noticeable responses of Bacillus subtilis cells to a range of
stress and starvation stimuli is the dramatic induction of about 150 SigB-dependent general …

Sigma factors provide promoter recognition specificity to RNA polymerase holoenzyme,
contribute to DNA strand separation, and then dissociate from the core enzyme following …

Staphylococci are a versatile genus of bacteria that are capable of causing acute and
chronic infections in diverse host species. The success of staphylococci as pathogens is due …

Antibiotic resistance is a key medical concern, with antibiotic use likely being an important
cause. However, here we describe an alternative route to clinically relevant antibiotic …