Recent advances in nanostructure/nanomaterial-assisted laser desorption/ionization mass spectrometry of low molecular mass compounds

H He, Z Guo, Y Wen, S Xu, Z Liu - Analytica chimica acta, 2019 - Elsevier
Laser desorption ionization mass spectrometry (LDI-MS) has been developed to be an
essential tool for the analysis and identification of a large variety of species, ranging from …

Mass spectrometry for multi-dimensional characterization of natural and synthetic materials at the nanoscale

X Huang, H Liu, D Lu, Y Lin, J Liu, Q Liu… - Chemical Society …, 2021 - pubs.rsc.org
Characterization of materials at the nanoscale plays a crucial role in in-depth understanding
the nature and processes of the substances. Mass spectrometry (MS) has characterization …

Surface charge controls the suborgan biodistributions of gold nanoparticles

SG Elci, Y Jiang, B Yan, ST Kim, K Saha, DF Moyano… - ACS …, 2016 - ACS Publications
Surface chemistry plays a deciding role in nanoparticle biodistribution, yet very little is
known about how surface chemistry influences the suborgan distributions of nanomaterials …

Mass spectrometry imaging reveals the sub-organ distribution of carbon nanomaterials

S Chen, C Xiong, H Liu, Q Wan, J Hou, Q He… - Nature …, 2015 - nature.com
Label and label-free methods to image carbon-based nanomaterials exist. However, label-
based approaches are limited by the risk of tag detachment over time, and label-free …

Gold‐Doped Covalent Organic Framework Reveals Specific Serum Metabolic Fingerprints as Point of Crohn's Disease Diagnosis

C Yang, H Yu, X Hu, H Chen, H Wu… - Advanced Functional …, 2021 - Wiley Online Library
Currently, most Crohn's disease (CD) patients suffer from serious complications and even
surgery due to delayed diagnosis; therefore, point‐of‐care diagnosis of CD is urgently …

Single-cell mass spectrometry imaging of multiple drugs and nanomaterials at organelle level

Y Meng, C Gao, Q Lu, S Ma, W Hang - Acs Nano, 2021 - ACS Publications
Mass spectrometry imaging (MSI) techniques make possible the spatial chemical
identification of analytes, especially for biological samples. As a universal energy source …

Noncovalent dual-locked near-infrared fluorescent probe for precise imaging of tumor via hypoxia/glutathione activation

XB Zhao, JY Kang, YP Shi - Analytical Chemistry, 2022 - ACS Publications
Stimulus-responsive fluorescent probes have broad applications in the early detection and
treatment of tumors and thus promote the personalized treatment of tumors and improve …

Hydroxyl-group-dominated graphite dots reshape laser desorption/ionization mass spectrometry for small biomolecular analysis and imaging

R Shi, X Dai, W Li, F Lu, Y Liu, H Qu, H Li, Q Chen… - Acs Nano, 2017 - ACS Publications
Small molecules play critical roles in life science, yet their facile detection and imaging in
physiological or pathological settings remain a challenge. Matrix-assisted laser desorption …

Large scale nanoparticle screening for small molecule analysis in laser desorption ionization mass spectrometry

GB Yagnik, RL Hansen, AR Korte, MD Reichert… - Analytical …, 2016 - ACS Publications
Nanoparticles (NPs) have been suggested as efficient matrixes for small molecule profiling
and imaging by laser-desorption ionization mass spectrometry (LDI-MS), but so far there has …

Mass Nanotags Mediate Parallel Amplifications on Nanointerfaces for Multiplexed Profiling of RNAs

Z Zhang, H Xu, Y Fan, X Zhang, W Wang, JJ Zhu… - Nano Letters, 2023 - ACS Publications
Multiplexed profiling of RNAs aids in a comprehensive understanding of multiparameter-
defined cellular processes and pathological states. We herein present a mass nanotags …