Comparative transcriptomics of high-altitude Vulpes and their low-altitude relatives

T Lyu, X Yang, C Zhao, L Wang, S Zhou… - Frontiers in Ecology …, 2022 - frontiersin.org
The harsh environment of Qinghai-Tibet Plateau (QTP) imposes strong selective stresses
(eg, hypoxia, high UV-radiation, and extreme temperature) to the native species, which have …

Tumor-derived hypoxic small extracellular vesicles promote endothelial cell migration and tube formation via ALS2/Rab5/β-catenin signaling

P Silva, N Hernandez, H Tapia, B Gaete, T Flores… - bioRxiv, 2024 - biorxiv.org
Tumor hypoxia has been associated with cancer progression, angiogenesis, and metastasis
via modifications in the release and cargo composition of extracellular vesicles secreted by …

Conditions-specific quantitative network rewiring of colon cancer-associated KRAS mutations in Caco-2 cell line

C Ternet - 2022 - researchrepository.ucd.ie
Ras is a key switch controlling cell behaviour. In the active, GTP-bound form, Ras can
interact with numerous effector proteins in a mutually exclusive manner, suggesting that …

[PDF][PDF] Détermination et caractérisation de nouveaux interacteurs pour la petite GTPase RAB25

R Larcher - 2022 - savoirs.usherbrooke.ca
Le trafic membranaire est un processus essentiel afin de réguler les fonctions et la survie
des cellules en permettant le transport des divers cargos vers leurs compartiments cibles …