The endothelium that lines the interior of blood vessels is directly exposed to blood flow. The
shear stress arising from blood flow is “sensed” by the endothelium and is “transduced” into …

Cardiovascular diseases account for more than half of total mortality before the age of 75 in
industrialized countries. To develop therapies promoting the compensatory growth of blood …

A three-dimensional and pulsatile blood flow in a human aortic arch and its three major
branches has been studied numerically for a peak Reynolds number of 2500 and a …

Capillary growth in skeletal muscle occurs via the dissimilar processes of abluminal
sprouting or longitudinal splitting, which can be initiated by muscle stretch and elevated …

Hemodynamic shear stress, the frictional force acting on vascular endothelial cells, is crucial
for endothelial homeostasis under normal physiological conditions. When discussing blood …

Arterial restenosis following stent deployment may be influenced by the local flow
environment within and around the stent. We have used computational fluid dynamics to …

Responses of vascular and lymphatic endothelial cells (ECs) to fluid shear stress (FSS) from
blood or lymphatic fluid flow govern the development, physiology, and diseases of these …

The endothelium responds to numerous chemical and mechanical factors in regulating
vascular tone, blood pressure, and blood flow. The endothelial volume-regulated anion …

Atherosclerosis depends on risk factors such as hyperlipidemia, smoking, hypertension and
diabetes. Although these risk factors are relatively constant throughout the arterial …

The quartz crystal microbalance (QCM) was used to monitor endothelial cell (EC) adhesion
on the gold surface of an oscillating quartz crystal contained in a QCM device. A number of …