Cyclical fate restriction: a new view of neural crest cell fate specification
RN Kelsh, K Camargo Sosa, S Farjami… - …, 2021 - journals.biologists.com
Neural crest cells are crucial in development, not least because of their remarkable
multipotency. Early findings stimulated two hypotheses for how fate specification and …
multipotency. Early findings stimulated two hypotheses for how fate specification and …
Zebrafish as a model system to study the mechanism of cutaneous wound healing and drug discovery: advantages and challenges
In humans, cutaneous wounds may heal without scars during embryogenesis. However, in
the adult phase, the similar wound may undergo a few events such as homeostasis, blood …
the adult phase, the similar wound may undergo a few events such as homeostasis, blood …
The role of wnt/β-catenin signalling in neural crest development in zebrafish
The neural crest (NC) is a multipotent cell population in vertebrate embryos with
extraordinary migratory capacity. The NC is crucial for vertebrate development and forms a …
extraordinary migratory capacity. The NC is crucial for vertebrate development and forms a …
Novel generic models for differentiating stem cells reveal oscillatory mechanisms
S Farjami, K Camargo Sosa… - Journal of The …, 2021 - royalsocietypublishing.org
Understanding cell fate selection remains a central challenge in developmental biology. We
present a class of simple yet biologically motivated mathematical models for cell …
present a class of simple yet biologically motivated mathematical models for cell …
Cell fate decisions in the neural crest, from pigment cell to neural development
The neural crest shows an astonishing multipotency, generating multiple neural derivatives,
but also pigment cells, skeletogenic and other cell types. The question of how this process is …
but also pigment cells, skeletogenic and other cell types. The question of how this process is …
MITF deficiency and oncogenic GNAQ each promote proliferation programs in zebrafish melanocyte lineage cells
GB Phelps, A Amsterdam, HR Hagen… - Pigment Cell & …, 2022 - Wiley Online Library
Uveal melanoma (UM) is the most common primary malignancy of the adult eye but lacks
any FDA‐approved therapy for the deadly metastatic disease. Thus, there is a great need to …
any FDA‐approved therapy for the deadly metastatic disease. Thus, there is a great need to …