Improved conventional and new approaches in the diagnosis of tuberculosis

B Dong, Z He, Y Li, X Xu, C Wang, J Zeng - Frontiers in Microbiology, 2022 - frontiersin.org
Tuberculosis (TB) is a life-threatening infectious disease caused by Mycobacterium
tuberculosis (M. tuberculosis). Timely diagnosis and effective treatment are essential in the …

Xpert MTB/RIF Ultra versus Xpert MTB/RIF for diagnosis of tuberculous pleural effusion: A systematic review and comparative meta-analysis

AN Aggarwal, R Agarwal, S Dhooria, KT Prasad… - PloS one, 2022 - journals.plos.org
Objective We compared diagnostic accuracy of pleural fluid Xpert MTB/RIF (Xpert) and Xpert
MTB/RIF Ultra (Ultra) assays for diagnosing tuberculous pleural effusion (TPE), through …

Diagnostic advances in childhood tuberculosis—improving specimen collection and yield of microbiological diagnosis for intrathoracic tuberculosis

E Wobudeya, M Bonnet, EG Walters, P Nabeta, R Song… - Pathogens, 2022 - mdpi.com
There is no microbiological gold standard for childhood tuberculosis (TB) diagnosis. The
paucibacillary nature of the disease, challenges in sample collection in young children, and …

Diagnosis of genitourinary tuberculosis: detection of mycobacterial lipoarabinomannan and MPT-64 biomarkers within urine extracellular vesicles by nano-based …

E Kamra, T Prasad, A Rais, B Dahiya, A Sheoran… - Scientific Reports, 2023 - nature.com
We detected a cocktail of Mycobacterium tuberculosis lipoarabinomannan (LAM) and MPT-
64 biomarkers within urine extracellular vesicles (EVs) of genitourinary TB (GUTB) patients …

[HTML][HTML] Nanoparticle formulations for therapeutic delivery, pathogen imaging and theranostic applications in bacterial infections

L Jiang, L Ding, G Liu - Theranostics, 2023 - ncbi.nlm.nih.gov
Pathogenic bacterial infections represent an ever-growing crisis, now significantly
threatening life expectancy across the worldwide population and thus novel approaches to …

Diagnosis of osteoarticular tuberculosis: multi-targeted loop-mediated isothermal amplification assay versus multiplex PCR

A Khan, E Kamra, R Singh, V Sharma, V Singh… - Future …, 2021 - Taylor & Francis
Aim: Diagnosis of osteoarticular tuberculosis (OATB) is quite challenging and there is an
urgent need to design a prompt and precise diagnostic test. Methods: We developed a multi …

Insight into diagnosis of female genital tuberculosis

B Dahiya, E Kamra, D Alam, M Chauhan… - Expert Review of …, 2022 - Taylor & Francis
Introduction Female genital tuberculosis (TB) is a common form of extrapulmonary TB
(EPTB) with varied clinical presentations, ie. infertility, pelvic pain, and menstrual …

Diagnosis of extrapulmonary tuberculosis by GeneXpert MTB/RIF Ultra assay

B Dahiya, N Mehta, A Soni… - Expert Review of Molecular …, 2023 - Taylor & Francis
Introduction Diagnosis of extrapulmonary tuberculosis (EPTB) is an arduous task owing to
different anatomical locations, unusual clinical presentations, and sparse bacillary load in …

The integration of gold nanoparticles with polymerase chain reaction for constructing colorimetric sensing platforms for detection of health-related DNA and proteins

W Wang, X Wang, J Liu, C Lin, J Liu, J Wang - Biosensors, 2022 - mdpi.com
Polymerase chain reaction (PCR) is the standard tool in genetic information analysis, and
the desirable detection merits of PCR have been extended to disease-related protein …

Diagnosis of peritoneal tuberculosis by real-time immuno-PCR assay based on detection of a cocktail of Mycobacterium tuberculosis CFP-10 and HspX proteins

P Mor, B Dahiya, S Sharma, A Sheoran… - Expert Review of …, 2022 - Taylor & Francis
Background Diagnosis of peritoneal TB is difficult owing to unusual clinical manifestations
and low sensitivities obtained with most of the available diagnostic modalities. Hence, there …