Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …

Tumor heterogeneity represents an ongoing challenge in the field of cancer therapy.
Heterogeneity is evident between cancers from different patients (inter-tumor heterogeneity) …

Despite the abundant ongoing research efforts, cancer remains one of the most challenging
diseases to treat globally. Due to the heterogenous nature of cancer, one of the major …

Cancer stemness, defined as the self-renewal and tumor-initiation potential of cancer stem
cells (CSCs), is a cancer biology property featuring activation of CSC signaling networks …

Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

Small populations of adult stem cells are responsible for the remarkable ability of the
epithelial lining of the intestine to be efficiently renewed and repaired throughout life. The …

Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men. Adenocarcinoma accounts for 90% of CRC cases. There has been …

Tumors are composed of different types of cancer cells that contribute to tumor
heterogeneity. Among these populations of cells, cancer stem cells (CSCs) play an …

Colorectal cancer is one of the most common cancers worldwide with high mortality. Distant
metastasis and relapse are major causes of patient death. Cancer stem cells (CSCs) play a …