Antithrombotic therapy in abdominal aortic aneurysm: beneficial or detrimental?

SJ Cameron, HM Russell… - Blood, The Journal of the …, 2018 - ashpublications.org
Abdominal aortic aneurysm (AAA) is a degenerative vascular pathology resulting in
significant morbidity and mortality in older adults due to rupture and sudden death. Despite …

[HTML][HTML] Intraluminal thrombus: Innocent bystander or factor in abdominal aortic aneurysm pathogenesis?

AJ Boyd - JVS-Vascular Science, 2021 - Elsevier
Abstract Background Abdominal aortic aneurysms (AAAs) represent a complex multifactorial
hemodynamic, thrombotic, and inflammatory process that can ultimately result in aortic …

A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms

P Di Achille, G Tellides… - Proceedings of the …, 2014 - royalsocietypublishing.org
Intraluminal thrombus (ILT) is present in over 75% of all abdominal aortic aneurysms (AAAs)
and probably contributes to the complex biomechanics and pathobiology of these lesions. A …

A general shear-dependent model for thrombus formation

A Yazdani, H Li, JD Humphrey… - PLoS computational …, 2017 - journals.plos.org
Modeling the transport, activation, and adhesion of platelets is crucial in predicting thrombus
formation and growth following a thrombotic event in normal or pathological conditions. We …

Intraluminal thrombus predicts rapid growth of abdominal aortic aneurysms

C Zhu, JR Leach, Y Wang, W Gasper, D Saloner… - Radiology, 2020 - pubs.rsna.org
Background Intraluminal thrombus (ILT) within abdominal aortic aneurysms (AAAs) may be
a potential marker for subsequent aneurysm growth. Purpose To investigate the role of ILT in …

Association of intraluminal thrombus, hemodynamic forces, and abdominal aortic aneurysm expansion using longitudinal CT images

BA Zambrano, H Gharahi, CY Lim, FA Jaberi… - Annals of biomedical …, 2016 - Springer
While hemodynamic forces and intraluminal thrombus (ILT) are believed to play important
roles on abdominal aortic aneurysm (AAA), it has been suggested that hemodynamic forces …

A three-dimensional phase-field model for multiscale modeling of thrombus biomechanics in blood vessels

X Zheng, A Yazdani, H Li, JD Humphrey… - PLoS computational …, 2020 - journals.plos.org
Mechanical interactions between flowing and coagulated blood (thrombus) are crucial in
dictating the deformation and remodeling of a thrombus after its formation in hemostasis. We …

A longitudinal comparison of hemodynamics and intraluminal thrombus deposition in abdominal aortic aneurysms

A Arzani, GY Suh, RL Dalman… - American Journal of …, 2014 - journals.physiology.org
Abdominal aortic aneurysm (AAA) is often accompanied by in traluminal thrombus (ILT),
which complicates AAA progression and risk of rupture. Patient-specific computational fluid …

Wall shear stress exposure time: a Lagrangian measure of near-wall stagnation and concentration in cardiovascular flows

A Arzani, AM Gambaruto, G Chen… - … and modeling in …, 2017 - Springer
Near-wall transport is of utmost importance in connecting blood flow mechanics with
cardiovascular disease progression. The near-wall region is the interface for biologic and …

Deep learning on multiphysical features and hemodynamic modeling for abdominal aortic aneurysm growth prediction

S Kim, Z Jiang, BA Zambrano, Y Jang… - … on Medical Imaging, 2022 - ieeexplore.ieee.org
Prediction of abdominal aortic aneurysm (AAA) growth is of essential importance for the
early treatment and surgical intervention of AAA. Capturing key features of vascular growth …