Introduction: Myeloid differentiation primary response protein 88 (MyD88) is a critical
adaptor protein involved in Toll-like and IL-1 receptor family signaling controlling innate …

In healthy individuals, infections of the central nervous system (CNS) are comparatively rare.
Based on the ability of microglial cells to phagocytose and kill pathogens and on clinical …

Infection and injury of the gut are associated with cell damage and release of molecules
such as extracellular adenosine 5′‐triphosphate (ATP), which is recognised by the …

Chronic neurologic infection with Toxoplasma gondii is relatively common in humans and is
one of the strongest known risk factors for schizophrenia. Nevertheless, the exact …

Toxoplasma gondii is a prevalent parasite of medical and veterinary importance.
Tachyzoïtes and bradyzoïtes are responsible for acute and chronic toxoplasmosis (AT and …

Toxoplasma gondii is an obligate intracellular parasite that is the etiologic agent responsible
for toxoplasmosis. Infection with T. gondii results in activation of nucleotide binding domain …

In most of the world Toxoplasma gondii is comprised of archetypal types (types I, II and III);
however, South America displays several non-archetypal strains. This study used an …

The host resistance against Toxoplasma gondii (T. gondii) infection is related to the initiation
of the immune response. The study aimed to investigate the role of the leucine-rich repeat …

Background Immune system cells are known to affect loss of neurons due to injury or
disease. Recruitment of immune cells following retinal/CNS injury has been shown to affect …

Toxoplasmosis is a neglected disease that affects millions of individuals worldwide.
Toxoplasma gondii infection is an asymptomatic disease, with lethal cases occurring mostly …