Pharmaceutical regulatory bodies increasingly require the implementation of systematic
approaches in pharmaceutical product development. Quality control methods play a key role …

The need for consistency in analytical method development reinforces the dependence of
pharmaceutical product development and manufacturing on robust analytical data. The …

This review presents the Analytical Quality by Design (AQbD) concept, an extension of
Quality by Design (QbD), which was introduced in 2004 by the US Food and Drug …

The adoption of Quality by Design (QbD) and Analytical Method Lifecycle Management
(AMLM) concepts to ensure the quality of pharmaceutical products has been applied and …

Purpurin-18 (P18) is one of the essential photosensitizers used in photodynamic therapy
(PDT), but its hydrophobicity causes easy coalescence and poor bioavailability. This study …

This article presents the development of a reversed-phase (RP) high-performance liquid
chromatographic (HPLC) method for determination of process-related impurities in a …

Background Apremilast is phosphodiesterase-4 and an immunomodulating agent used for
treatment of refractory psoriatic arthritis. Methods The reversed-phase high-performance …

Degradation studies of drug give insightful information about the intrinsic stability of the
molecule, the possible degradents formed during shelf life and thus, aid in the subsequent …

Background: For the development of robust analytical methods, Analytical-Qualityby-Design
(AQbD)-based testing methods have been found to be more suited than other one factorial …

Photodynamic therapy (PDT) is a non-invasive and tumour-specific therapy.
Photosensitizers (PSs)(essential ingredients in PDT) aggregate easily owing to their …