Severe acute pancreatitis (SAP), a serious inflammatory disease of the pancreas, can easily
lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction …

Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate
their structure and function. Glycans modify proteins required for regulation of immune cells …

Numerous cellular processes are controlled by the proteasome, a multicatalytic protease in
the cytosol and nucleus of all eukaryotic cells, through regulated protein degradation. The …

Secreted, plasma membrane, and resident proteins of the secretory pathway are
synthesized in the endoplasmic reticulum (ER) where they undergo post-translational …

Endoplasmic reticulum (ER) stress and subsequent apoptosis played vital role in liver injury
and dysfunction. The aim of this study was to investigate the protective effect and …

A proper execution of basic cellular functions requires well-controlled homeostasis including
correct protein folding. Endoplasmic reticulum (ER) implements such functions by protein …

Although only a small number of primordial follicles are known to be selectively activated
during female reproductive cycles, the mechanisms that trigger this recruitment remain …

Abstract Treatment of acute pancreatitis (AP) and chronic pancreatitis (CP) remains
problematic due to a lack of knowledge about disease-specific regulatory targets and …

Pancreatic acinar cells rely on PTF1 and other transcription factors to deploy their
transcriptional program. We identify NFIC as a NR5A2 interactor and regulator of acinar …

Human exposure to silica nanoparticles (SiNPs) has been widely applied as vehicles for
drug delivery and cellular manipulations in nanoneuromedicine. SiNPs may cause adverse …