Legionnaires' Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella
S Mondino, S Schmidt, M Rolando… - Annual Review of …, 2020 - annualreviews.org
Legionella species are environmental gram-negative bacteria able to cause a severe form of
pneumonia in humans known as Legionnaires' disease. Since the identification of …
pneumonia in humans known as Legionnaires' disease. Since the identification of …
Post-translational regulation of ubiquitin signaling
L Song, ZQ Luo - Journal of Cell Biology, 2019 - rupress.org
Ubiquitination regulates many essential cellular processes in eukaryotes. This post-
translational modification (PTM) is typically achieved by E1, E2, and E3 enzymes that …
translational modification (PTM) is typically achieved by E1, E2, and E3 enzymes that …
ADP-ribosylation, a multifaceted posttranslational modification involved in the control of cell physiology in health and disease
B Lüscher, M Bütepage, L Eckei, S Krieg… - Chemical …, 2018 - ACS Publications
Posttranslational modifications (PTMs) regulate protein functions and interactions. ADP-
ribosylation is a PTM, in which ADP-ribosyltransferases use nicotinamide adenine …
ribosylation is a PTM, in which ADP-ribosyltransferases use nicotinamide adenine …
Legionella and Coxiella effectors: strength in diversity and activity
J Qiu, ZQ Luo - Nature Reviews Microbiology, 2017 - nature.com
Legionella pneumophila and Coxiella burnetii are two evolutionarily related intracellular
pathogens that use the Dot/Icm type IV secretion system to translocate effectors into host …
pathogens that use the Dot/Icm type IV secretion system to translocate effectors into host …
Pathogenicity and Virulence of Legionella: Intracellular replication and host response
Bacteria of the genus Legionella are natural pathogens of amoebae that can cause a severe
pneumonia in humans called Legionnaires' Disease. Human disease results from inhalation …
pneumonia in humans called Legionnaires' Disease. Human disease results from inhalation …
Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin catalysed glutamylation
The family of bacterial SidE enzymes catalyses phosphoribosyl-linked serine ubiquitination
and promotes infectivity of Legionella pneumophila, a pathogenic bacteria that causes …
and promotes infectivity of Legionella pneumophila, a pathogenic bacteria that causes …
Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases
Enzymes with a protein kinase fold transfer phosphate from adenosine 5′-triphosphate
(ATP) to substrates in a process known as phosphorylation. Here, we show that the …
(ATP) to substrates in a process known as phosphorylation. Here, we show that the …
Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
The bacterial pathogen Legionella pneumophila creates an intracellular niche permissive
for its replication by extensively modulating host-cell functions using hundreds of effector …
for its replication by extensively modulating host-cell functions using hundreds of effector …
The Sde phosphoribosyl–linked ubiquitin transferases protect the Legionella pneumophila vacuole from degradation by the host
Legionella pneumophila grows intracellularly within the membrane-bound Legionella-
containing vacuole (LCV) established by proteins translocated via the bacterial type IV …
containing vacuole (LCV) established by proteins translocated via the bacterial type IV …
The ubiquitin codes in cellular stress responses
Ubiquitination/ubiquitylation, one of the most fundamental post-translational modifications,
regulates almost every critical cellular process in eukaryotes. Emerging evidence has shown …
regulates almost every critical cellular process in eukaryotes. Emerging evidence has shown …