The recent developments of nuclear medicine in oncology have involved numerous
investigations of novel specific tumor-targeting radiopharmaceuticals as a major area of …

Inert microspheres, labeled with several radionuclides, have been developed during the last
two decades for the intra-arterial treatment of liver tumors, generally called Selective …

Although MRI produces images with an unprecedented spatial and temporal resolution,
early experiments showed that the diagnostic value might be improved significantly by …

In recent years, nanoparticles have played an ever increasing role in biomedical research
and clinical applications. The unique physical properties of nanomaterials are being …

The use of ultrasound contrast agents as local drug delivery systems continues to grow.
Current limitations are the amount of drug that can be incorporated as well as the efficiency …

Background Intra-arterial radioembolization with yttrium-90 microspheres (90 Y-RE) is an
increasingly used therapy for patients with unresectable liver malignancies. Over the last …

Transarterial radioembolization (TARE) is a promising technology in hepatocellular
carcinoma (HCC) therapy, which utilizes radionuclide-labeled microspheres to achieve …

Objectives To demonstrate the feasibility of MRI-based assessment of the intrahepatic Ho-
PLLA-MS biodistribution after radioembolisation in order to estimate the absorbed radiation …

Radioactive holmium-166 loaded poly (l-lactic acid) microspheres are promising systems for
the treatment of liver malignancies. The microspheres are loaded with holmium …

Trans-arterial radioembolization (TARE) therapy confronts significant technical challenges in
the preparation of metal nuclide-labeled microsphere carriers, the development of stable …