The term 'fibroblast'often serves as a catch-all for a diverse array of mesenchymal cells,
including perivascular cells, stromal progenitor cells and bona fide fibroblasts. Although …

Signalling from the extracellular matrix (ECM) is a fundamental cellular input that sustains
proliferation, opposes cell death and regulates differentiation. Through integrins, cells …

Neural stem cells are multipotent cells with the ability to differentiate into neurons,
astrocytes, and oligodendrocytes. Lineage specification is strongly sensitive to the …

Physical factors in the local cellular microenvironment, including cell shape and geometry,
matrix mechanics, external mechanical forces, and nanotopographical features of the …

Mesenchymal stem cells (MSCs) display substantial cell-to-cell variation. This heterogeneity
manifests among donors, among tissue sources, and within cell populations. Such pervasive …

Principles of Regenerative Medicine, Third Edition, details the technologies and advances
applied in recent years to strategies for healing and generating tissue. Contributions from a …

Extracellular matrix can influence stem cell choices, such as self‐renewal, quiescence,
migration, proliferation, phenotype maintenance, differentiation, or apoptosis. Three aspects …

In vivo and in vitro studies have demonstrated the positive role that ultrasound can play in
the enhancement of fracture healing or in the reactivation of a failed healing process. We …

Low back pain (LBP) is a chronic condition that can affect up to 80% of the global
population. It is the number one cause of disability worldwide and has enormous …

Lung vascular endothelial barrier disruption and the accompanying inflammation are
primary pathogenic features of acute lung injury (ALI); however, the basis for the …