Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …

Management of paediatric extracranial germ-cell tumours carries a unique set of challenges.
Germ-cell tumours are a heterogeneous group of neoplasms that present across a wide age …

Purpose: Testis cancer is the most common solid malignancy in young males. The purpose
of this guideline is to provide a useful reference on the effective evidence-based treatment of …

Background Comparative assessment of treatment results in paediatric hepatoblastoma
trials has been hampered by small patient numbers and the use of multiple disparate …

Background Although teratomas are the most common histologic subtype of childhood
ovarian germ cell tumors, their appropriate treatment in this age group still remains unclear …

Germ cell tumors (GCTs) arising in infants, children, and adolescents present a set of special
challenges. GCTs make up about 3% of malignancies in children aged 0–18 and nearly …

During the past 35 years, survival rates for children with extracranial malignant germ cell
tumors (GCTs) have increased significantly. Success has been achieved primarily through …

Germ cell tumors (GCTs) are rare in childhood, representing only 3.5% of childhood
cancers, but a common malignancy in adolescents and young adults (AYAs), accounting for …

Simple Summary The article presents the role of alpha-fetoprotein in the diagnosis and
monitoring of treatment for selected genetic diseases and early childhood cancers. The …

Objective: To evaluate prognostic factors in pediatric patients with gonadal germ cell tumors
(GCT). Methods: Patients< 18 years with ovarian and testicular GCT (respectively OGCT and …