Computational models can be applied to optimize treatment schedules and model treatment
responses in cancer therapy. In this Review, we provide an overview of such computational …

Cancer cells metabolize glucose through metabolic pathways that differ from those used by
healthy and differentiated cells. In particular, tumours have been shown to consume more …

Cancer metastasis relies on an orchestration of traits driven by different interacting functional
modules, including metabolism and epithelial-mesenchymal transition (EMT). During …

Colorectal cancer (CRC) represents a significant global health burden, with high incidence
and mortality rates worldwide. Recent progress in research highlights the distinct clinical …

This study describes our attempts to generate a sustainable cell culture of Macrobrachium
rosenbergii. We present here a continuous longitudinal study on the embryonic primary cell …

Data from cell viability assays, which measure cumulative division and death events in a
population and reflect substantial cellular heterogeneity, are widely available. However …

Cancer is one of the leading causes of disease related death worldwide. Since the discovery
of the genomic origins of cancer, targeted therapy has been developed towards specific …

Metastasis is the leading cause of cancer-related deaths. While cancer and metastasis have
been studied for many years there is still much to learn, particularly with regards to how …

Due to its complexity, cancer continues to be one of the leading causes of death worldwide.
The creation of suitable preventative practices and innovative therapies is limited by the lack …

Most tumors are characterized by increased glucose uptake and lactate production, a
phenomenon known as aerobic glycolysis. Active glucose uptake and glycolysis can provide …